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Article
Genetic association of CHEK2, GSTP1, and ERCC1 with glioblastoma in the Han Chinese population
Glioblastoma (GBM), a deadly brain tumor, is the most malignant glioma. It mainly occurs in adults and occurs significantly more in males than in females. We genotyped 19 tag single nucleotide polymorphisms (t...
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Article
RTEL1 and TERT polymorphisms are associated with astrocytoma risk in the Chinese Han population
Common variants of multiple genes play a role in glioma onset. However, research related to astrocytoma, the most common primary brain neoplasm, is rare. In this study, we chose 21 tagging SNPs (tSNPs), previo...
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Article
Astragaloside IV prevents MPP+-induced SH-SY5Y cell death via the inhibition of Bax-mediated pathways and ROS production
Parkinson’s disease (PD) is characterized by a progressive degeneration of dopaminergic neurons in the substantia nigra. Oxidative stress and neural degeneration are suggested to be involved in the pathogenesi...
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Article
Potential role of Jun activation domain-binding protein 1 and phosphorylated p27 expression in prognosis of glioma
To investigate whether Jun activation domain-binding protein 1 (Jab1) expression is correlated with p27 protein and its phosphorylation status as well as how it might be clinically relevant in glioma, we carri...
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Article
Open AccessReduced expression of SMAD4 in gliomas correlates with progression and survival of patients
To examine the expression of SMAD4 at gene and protein levels in glioma samples with different WHO grades and its association with survival.