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  1. Article

    Open Access

    Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance

    Posttranslational modification dramatically enhances protein complexity, but the function and precise mechanism of novel lysine acylation modifications remain unknown. Chemoresistance remains a daunting challe...

    Yan He, Can-Can Zheng, **g Yang, Shu-Jun Li, Tao-Yang Xu, **an Wei… in Cell Discovery (2023)

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    Article

    Lysine 2-hydroxyisobutyrylation of NAT10 promotes cancer metastasis in an ac4C-dependent manner

    Posttranslational modifications add tremendous complexity to proteomes; however, gaps remain in knowledge regarding the function and regulatory mechanism of newly discovered lysine acylation modifications. Her...

    Long Liao, Yan He, Shu-Jun Li, **ao-Mei Yu, Zhi-Chao Liu, Yi-Yao Liang… in Cell Research (2023)