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  1. Article

    Open Access

    The assessment of left ventricular volume and function in gated small animal 18F-FDG PET/CT imaging: a comparative study of three commercially available software tools

    Several software tools have been developed for gated PET imaging that use distinct algorithms to analyze tracer uptake, myocardial perfusion, and left ventricle volumes and function. Studies suggest that diffe...

    Mathias J. Zacherl, Agus Simenhandra, Magdalena Lindner in EJNMMI Research (2023)

  2. Article

    Open Access

    Detection of apoptosis by [18F]ML-10 after cardiac ischemia–reperfusion injury in mice

    Myocardial infarction leads to ischemic heart disease and cell death, which is still a major obstacle in western society. In vivo imaging of apoptosis, a defined cascade of cell death, could identify myocardia...

    Maximilian Fischer, Mathias J. Zacherl, Jessica Olivier in Annals of Nuclear Medicine (2023)

  3. Article

    Open Access

    Comparison of transient and permanent LAD ligation in mice using 18F-FDG PET imaging

    Animal models for myocardial injuries represent important cornerstones in cardiovascular research to monitor the pathological processes and therapeutic approaches. We investigated the association of 18F-FDG de...

    Maximilian Fischer, Tobias Weinberger, Denise Messerer in Annals of Nuclear Medicine (2022)

  4. Article

    Open Access

    Feasibility of short imaging protocols for [18F]PI-2620 tau-PET in progressive supranuclear palsy

    Dynamic 60-min positron emission tomography (PET) imaging with the novel tau radiotracer [18F]PI-2620 facilitated accurate discrimination between patients with progressive supranuclear palsy (PSP) and healthy con...

    Mengmeng Song, Maximilian Scheifele in European Journal of Nuclear Medicine and M… (2021)

  5. No Access

    Article

    In-vivo comparison of the acute retention of stem cell derivatives and fibroblasts after intramyocardial transplantation in the mouse model

    Various strategies have been applied to increase the engraftment of an intramyocardial cell transplant (Tx) to treat ischemic myocardium. Thereby, co-transplanted fibroblasts (FB) improve the long-term surviva...

    Cajetan Lang, Sebastian Lehner in European Journal of Nuclear Medicine and M… (2014)

  6. No Access

    Article

    Positron emission tomography based in-vivo imaging of early phase stem cell retention after intramyocardial delivery in the mouse model

    To establish PET as a tool for in-vivo quantification and monitoring of intramyocardially transplanted stem cells after labelling with FDG in mice with induced myocardial infarction.

    Cajetan Lang, Sebastian Lehner in European Journal of Nuclear Medicine and M… (2013)

  7. No Access

    Article

    A prototype high-resolution animal positron tomograph with avalanche photodiode arrays and LSO crystals

    To fully utilize positron emission tomography (PET) as a non-invasive tool for tissue characterization, dedicated instrumentation is being developed which is specially suited for imaging mice and rats. Semicon...

    Sibylle I. Ziegler, Bernd J. Pichler, Guido Boening in European Journal of Nuclear Medicine (2001)