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Article

Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau

Augmenting the brain clearance of toxic oligomers with small molecule modulators constitutes a promising therapeutic concept against tau deposition. However, there has been no test of this concept in animal mo...

Matthias Brendel, Maximilian Deussing, Tanja Blume… in Alzheimer's Research & Therapy (2019)