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LncRNA BCAN-AS1 stabilizes c-Myc via N6-methyladenosine-mediated binding with SNIP1 to promote pancreatic cancer

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  1. Article

    Open Access

    NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization

    5-Methylcytosine (m5C) is a posttranscriptional RNA modification participating in many critical bioprocesses, but its functions in human cancer remain unclear. Here, by detecting the transcriptome-wide m5C profil...

    Jiachun Su, Guandi Wu, Ying Ye, Jialiang Zhang, Lingxing Zeng, Xudong Huang… in Oncogene (2021)

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  2. Article

    Open Access

    LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling

    The molecular mechanism underlying pancreatic ductal adenocarcinoma (PDAC) malignancy remains unclear. Here, we characterize a long intergenic non-coding RNA LINC00842 that plays a role in PDAC progression. LINC0...

    Xudong Huang, Ling Pan, Zhixiang Zuo, Mei Li, Lingxing Zeng… in Nature Communications (2021)

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