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    Article

    RNA m6A regulates transcription via DNA demethylation and chromatin accessibility

    Transcriptional regulation, which integrates chromatin accessibility, transcription factors and epigenetic modifications, is crucial for establishing and maintaining cell identity. The interplay between differ...

    Shuang Deng, Jialiang Zhang, Jiachun Su, Zhixiang Zuo, Lingxing Zeng in Nature Genetics (2022)

  2. Article

    Open Access

    NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization

    5-Methylcytosine (m5C) is a posttranscriptional RNA modification participating in many critical bioprocesses, but its functions in human cancer remain unclear. Here, by detecting the transcriptome-wide m5C profil...

    Jiachun Su, Guandi Wu, Ying Ye, Jialiang Zhang, Lingxing Zeng, Xudong Huang in Oncogene (2021)