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  1. No Access

    Article

    LncRNA BCAN-AS1 stabilizes c-Myc via N6-methyladenosine-mediated binding with SNIP1 to promote pancreatic cancer

    C-Myc overexpression contributes to multiple hallmarks of human cancer but directly targeting c-Myc is challenging. Identification of key factors involved in c-Myc dysregulation is of great significance to dev...

    Guandi Wu, Jiachun Su, Lingxing Zeng, Shuang Deng… in Cell Death & Differentiation (2023)

  2. Article

    Open Access

    NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization

    5-Methylcytosine (m5C) is a posttranscriptional RNA modification participating in many critical bioprocesses, but its functions in human cancer remain unclear. Here, by detecting the transcriptome-wide m5C profil...

    Jiachun Su, Guandi Wu, Ying Ye, Jialiang Zhang, Lingxing Zeng, Xudong Huang… in Oncogene (2021)

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