2 Result(s)

Article

Putative novel CSF biomarkers of Alzheimer’s disease based on the novel concept of generic protein misfolding and proteotoxicity: the PRAMA cohort

Alessandra Bigi, Giulia Fani, Valentina Bessi… in Translational Neurodegeneration (2024)

Article

Misfolded protein oligomers induce an increase of intracellular Ca²⁺ causing an escalation of reactive oxidative species

Alzheimer's disease is characterized by the accumulation in the brain of the amyloid β (Aβ) peptide in the form of senile plaques. According to the amyloid hypothesis, the aggregation process of Aβ also genera...

Giulia Fani, Chiara Ester La Torre… in Cellular and Molecular Life Sciences (2022)