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    Open Access

    Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species

    Alzheimer's disease is characterized by the accumulation in the brain of the amyloid β (Aβ) peptide in the form of senile plaques. According to the amyloid hypothesis, the aggregation process of Aβ also genera...

    Giulia Fani, Chiara Ester La Torre in Cellular and Molecular Life Sciences (2022)