3 Result(s)
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Gie Ken Dror
Public Health
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Article
Open AccessMarkov chain Monte Carlo Gibbs sampler approach for estimating haplotype frequencies among multiple malaria infected human blood samples
Malaria patients can have two or more haplotypes in their blood sample making it challenging to identify which haplotypes they carry. In addition, there are challenges in measuring the type and frequency of re...
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Article
Open AccessMarkov chain Monte Carlo and expectation maximization approaches for estimation of haplotype frequencies for multiply infected human blood samples
Haplotypes are important in anti-malarial drug resistance because genes encoding drug resistance may accumulate mutations at several codons in the same gene, each mutation increasing the level of drug resistan...
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Article
A genetic instrument for Mendelian randomization of fibrinogen
Mendelian randomization studies on fibrinogen commonly use a single genetic variant as an instrument, but this may explain only a small proportion of the total phenotypic variance. We examined the contribution...
