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  1. Article

    Open Access

    Markov chain Monte Carlo and expectation maximization approaches for estimation of haplotype frequencies for multiply infected human blood samples

    Haplotypes are important in anti-malarial drug resistance because genes encoding drug resistance may accumulate mutations at several codons in the same gene, each mutation increasing the level of drug resistan...

    Gie Ken-Dror, Ian M. Hastings in Malaria Journal (2016)

  2. Article

    Open Access

    Markov chain Monte Carlo Gibbs sampler approach for estimating haplotype frequencies among multiple malaria infected human blood samples

    Malaria patients can have two or more haplotypes in their blood sample making it challenging to identify which haplotypes they carry. In addition, there are challenges in measuring the type and frequency of re...

    Gie Ken-Dror, Pankaj Sharma in Malaria Journal (2021)