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    Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis

    Epigenetic plasticity is a pivotal factor that drives metastasis. Here, we show that the promoter of the gene that encodes the ubiquitin ligase subunit FBXL7 is hypermethylated in advanced prostate and pancrea...

    Loredana Moro, Daniele Simoneschi, Emma Kurz, Arnaldo A. Arbini… in Nature Cell Biology (2020)