3 Result(s)
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Article
Open AccessTime-varying SUVr reflects the dynamics of dopamine increases during methylphenidate challenges in humans
Dopamine facilitates cognition and is implicated in reward processing. Methylphenidate, a dopamine transporter blocker widely used to treat attention-deficit/hyperactivity disorder, can have rewarding and addi...
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Article
Open AccessStriatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment
Eye-blink rate has been proposed as a biomarker of the brain dopamine system, however, findings have not been consistent. This study assessed the relationship between blink rates, measured after oral placebo) ...
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Article
Open AccessCortical D1 and D2 dopamine receptor availability modulate methylphenidate-induced changes in brain activity and functional connectivity
Dopamine signaling plays a critical role in sha** brain functional network organization and behavior. Prominent theories suggest the relative expression of D1- to D2-like dopamine receptors shapes excitatory...
