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    Human uracil–DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

    Activation-induced cytidine deaminase (AID) is a 'master molecule' in immunoglobulin (Ig) class-switch recombination (CSR) and somatic hypermutation (SHM) generation, AID deficiencies are associated with hyper...

    Kohsuke Imai, Geir Slupphaug, Wen-I Lee, Patrick Revy… in Nature Immunology (2003)