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Open AccessP95: Effect of Chronic Inflammation Inhibition with Salsalate on Aortic Stiffness and Vascular Endothelial Function in Older Adults: A Randomized Controlled Study
Chronic activation of the proinflammatory transcription factor nuclear factor kappa-B (NFkB) is linked to age-associated vascular dysfunction. Acute inhibition of NFkB with high-dose salsalate (>4g), a non-ace...
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Article
Open AccessP102 Large Artery Stiffness is Associated with Lower Brain pH and Memory Performance in Middle-aged and Older Adults
Large artery stiffening is a novel risk factor for cognitive impairment including Alzheimer’s disease. Loss of impedance mismatch between central and cerebral arteries promotes cerebrovascular dysfunction via ...