37 Result(s)
within
Gao **ang
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessOptimization of preparation conditions and performance of a new degradable soil water retaining agent
Using polyaspartic acid (PAsp) and bentonite (BT) as the main raw materials, a new type of degradable soil water retaining agent (PAsp-AA/BT) was synthesized by microwave radiation. The optimum synthesis condi...
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Open AccessThe cavitation characteristics of aerospace high-speed centrifugal pumps with different tip clearance
This study investigates the Tip Clearance Cavitation (TCC) characteristics of three different Tip Clearances (TC) (0.4, 0.6, 0.8) and five inlet negative pressure conditions Pj = (− 20–60)kPa to improve the re...
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Article
Open AccessInterplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas
Stimulating the innate immune system has been explored as a therapeutic option for the treatment of gliomas. Inactivating mutations in ATRX, defining molecular alterations in IDH-mutant astrocytomas, have been im...
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Open AccessMetabolomics profiling in predicting of post-herpetic neuralgia induced by varicella zoster
To explore potential metabolomics biomarkers in predicting post-herpetic neuralgia (PHN) induced by herpes zoster (HZ). A total of 90 eligible patients were prospectively enrolled and assigned into an acute pa...
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Article
Open AccessEthnicity-specific association between TERT rs2736100 (A > C) polymorphism and lung cancer risk: a comprehensive meta-analysis
The rs2736100 (A > C) polymorphism of the second intron of Telomerase reverse transcriptase (TERT) has been confirmed to be closely associated with the risk of Lung cancer (LC), but there is still no unified conc...
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Open AccessNovel characteristics for immunophenotype, FISH pattern and molecular cytogenetics in synovial sarcoma
As a rare and highly aggressive soft tissue sarcoma, the new immunophenotype, atypical FISH pattern and relevant molecular cytogenetics of synovial sarcoma (SS) remain less known, although it is characteristic...
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Open AccessThe correlation between high-density lipoprotein cholesterol and bone mineral density in adolescents: a cross-sectional study
Recent studies have shown a correlation between high-density lipoprotein cholesterol (HDL-C) and bone mineral density (BMD) in adults, but their relationship is unclear in adolescents. This study aimed to expl...
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Article
Targeting TBK1 to overcome resistance to cancer immunotherapy
Despite the success of PD-1 blockade in melanoma and other cancers, effective treatment strategies to overcome resistance to cancer immunotherapy are lacking1,2. Here we identify the innate immune kinase TANK-bin...
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Open AccessPrevalence and factors associated with hepatitis C among pregnant women in China: a cross-sectional study
Pregnant women infected with HCV should be given attention due to their special physiological stage and the effect on offspring health. To examine the prevalence of HCV infection among pregnant women in part o...
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Open AccessSpatial–temporal changes in the degradation of marshes over the past 67 years
Agricultural reclamation is widely regarded as a primary cause of marshes degradation. However, the process of marshes degradation on different geomorphology has rarely explored, which fail to explain the mars...
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Article
Open AccessPathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blockade in metastatic melanoma
Both genomic and transcriptomic signatures have been developed to predict responses of metastatic melanoma to immune checkpoint blockade (ICB) therapies; however, most of these signatures are derived from pre-...
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Article
Open AccessAssisting scalable diagnosis automatically via CT images in the combat against COVID-19
The pandemic of Coronavirus Disease 2019 (COVID-19) is causing enormous loss of life globally. Prompt case identification is critical. The reference method is the real-time reverse transcription PCR (RT-PCR) a...
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Open AccessVery low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy
Several immunotherapy clinical trials in recurrent glioblastoma have reported long-term survival benefits in 10–20% of patients. Here we perform genomic analysis of tumor tissue from recurrent WHO grade IV gli...
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Article
Open AccessAuthor Correction: Light-powered Escherichia coli cell division for chemical production
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessLight-powered Escherichia coli cell division for chemical production
Cell division can perturb the metabolic performance of industrial microbes. The C period of cell division starts from the initiation to the termination of DNA replication, whereas the D period is the bacterial...
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Open AccessSwitched-capacitor-convertors based on fractal design for output power management of triboelectric nanogenerator
Owing to the advantages of integration and being magnet-free and light-weight, the switched-capacitor-convertor plays an increasing role compared to traditional transformer in some specific power supply system...
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Article
Open AccessAll-Optical Naked-Eye Ghost Imaging
Ghost imaging is usually based on the optoelectronic process and electronic computing. A new ghost imaging approach is put forward in the paper that avoids any optoelectronic or electronic process. Instead, th...
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Article
Open AccessFunctional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer
Chronic inflammation and chromosome aneuploidy are major traits of primary liver cancer (PLC), which represent the second most common cause of cancer-related death worldwide. Increased cancer fitness and aggre...
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Article
Open AccessB cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma
Tumor associated inflammation predicts response to immune checkpoint blockade in human melanoma. Current theories on regulation of inflammation center on anti-tumor T cell responses. Here we show that tumor as...
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Open AccessUp-regulation of heat shock protein 27 inhibits apoptosis in lumbosacral nerve root avulsion-induced neurons
Lumbosacral nerve root avulsion leads to widespread death of neurons in the anterior horn area of the injured spinal cord, which results in dysfunction in the lower extremities. Heat shock protein 27 (Hsp27) h...
