13 Result(s)
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Gabriella Andreotti
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Article
Genetic determinants of serum lipid levels in Chinese subjects: a population-based study in Shanghai, China
We examined the associations between 21 single nucleotide polymorphisms (SNPs) of eight lipid metabolism genes and lipid levels in a Chinese population. This study was conducted as part of a population-based s...
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Article
Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohort
Obesity is associated with increased risks of several cancers including colon and female breast. Pesticide use in agricultural populations has also been linked with higher risks of various cancers. However, th...
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Article
Medical history and the risk of biliary tract cancers in Shanghai, China: implications for a role of inflammation
Several lines of evidence suggest that inflammation may play a role in the etiology of biliary tract cancers. To examine further the role of inflammation, we evaluated the associations between self-reported in...
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Article
Using multiple imputation to assign pesticide use for non-responders in the follow-up questionnaire in the Agricultural Health Study
The Agricultural Health Study (AHS), a large prospective cohort, was designed to elucidate associations between pesticide use and other agricultural exposures and health outcomes. The cohort includes 57,310 pe...
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Open AccessInflammatory gene variants and the risk of biliary tract cancers and stones: a population-based study in China
Genetic variants in inflammation-related genes have been associated with biliary stones and biliary tract cancers in previous studies.
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Article
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer
Rachael Stolzenberg-Solomon, Laufey Amundadottir and colleagues report a genome-wide association study of pancreatic cancer. They identify four new susceptibility loci.
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Article
Open AccessGenome-wide association study identifies multiple risk loci for renal cell carcinoma
Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four ...
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Open AccessA prospective study of cancer risk among Agricultural Health Study farm spouses associated with personal use of organochlorine insecticides
Organochlorine insecticides (OCs) have historically been used worldwide to control insects, although most have now been banned in developed countries. Evidence for an association between OC exposures and cance...
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Article
Open AccessGenome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer
In 2020, 146,063 deaths due to pancreatic cancer are estimated to occur in Europe and the United States combined. To identify common susceptibility alleles, we performed the largest pancreatic cancer GWAS to d...
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Open AccessTobacco, alcohol use and risk of hepatocellular carcinoma and intrahepatic cholangiocarcinoma: The Liver Cancer Pooling Project
While tobacco and alcohol are established risk factors for hepatocellular carcinoma (HCC), the most common type of primary liver cancer, it is unknown whether they also increase the risk of intrahepatic cholan...
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Article
Cancer incidence in the Agricultural Health Study after 20 years of follow-up
To evaluate cancer incidence in the Agricultural Health Study (AHS), a cohort of private pesticide applicators, their spouses, and commercial applicators, based on 12,420 cancers, adding 5,989 cancers, and 9 y...
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Article
An algorithm for quantitatively estimating non-occupational pesticide exposure intensity for spouses in the Agricultural Health Study
Residents of agricultural areas experience pesticide exposures from sources other than direct agricultural work. We developed a quantitative, active ingredient-specific algorithm for cumulative (adult, married...
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Article
Open AccessPesticide exposure and risk of aggressive prostate cancer among private pesticide applicators
Prostate cancer (PCa) is one of the most commonly diagnosed cancers among men in developed countries; however, little is known about modifiable risk factors. Some studies have implicated organochlorine and org...
