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  1. Article

    Open Access

    Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma

    Senescent cells may promote tumour progression through the activation of a senescence-associated secretory phenotype (SASP), whether these cells are capable of initiating tumourigenesis in vivo is not known. E...

    Jose Mario Gonzalez-Meljem, Scott Haston, Gabriela Carreno in Nature Communications (2017)

  2. Article

    Open Access

    Activated WNT signaling in postnatal SOX2-positive dental stem cells can drive odontoma formation

    In common with most mammals, humans form only two dentitions during their lifetime. Occasionally, supernumerary teeth develop in addition to the normal complement. Odontoma represent a small group of malformat...

    Guilherme M. Xavier, Amanda L. Patist, Chris Healy, Ankita Pagrut in Scientific Reports (2015)