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Article
pCOR: a new design of plasmid vectors for nonviral gene therapy
A totally redesigned host/vector system with improved properties in terms of safety has been developed. The pCOR plasmids are narrow-host range plasmid vectors for nonviral gene therapy. These plasmids contain...
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Chapter
Peptide Libraries in Cellular Immune Recognition
Protective immunity against microbial pathogens is connected with the ability to discriminate between self and non-self. Vertebrates have evolved an adaptive immune system in which specialized white blood cell...
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Chapter and Conference Paper
Synthetic Lipopeptides of Bacterial Origin as Novel and Efficient Adjuvants for Parenteral and Oral Immunization
Lipopeptides of bacterial origin constitute potent immunoadjuvants in vitro and in vivo when given in combination with antigens [1–3]. Parenteral application of the lipopeptide P3CSK4, shown in Fig. 1, enhanced t...
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Article
Fine map** of HIV-1 Nef-epitopes by monoclonal antibodies
A panel of newly isolated murine monoclonal antibodies is described which are specific for the Nef protein of the human immunodeficiency virus type 1 (HIV-1). Epitope map** using recombinant Nef-related prot...
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Article
The value of the thromboelastogram as means of monitoring the sub-cutaneous preventive action of calcium heparinate
The index of the thrombodynamic potential (I.T.P.) as one of the biological means of controlling the prophylactic effect of sub-cutaneous injections of Calcium Heparinate has been studied in 34 spinal cord inj...