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Article
Does a chemically symmetric bond pattern induce a symmetric conformation of lecithin molecules in membranes?
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Probing the Mechanism of Pancreatic Phospholipase A2 with the Aid of Recombinant DNA Techniques
Phospholipase A2 (E.C. 3.1.1.4) attacks the acyl ester bond at position 2 of 3-sn-phosphoglycerides (van Deenen en de Haas, 1963). The in-vivo importance of phospholipase A2 (PLA) is reflected by the fact that th...
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Article
Solution structure of porcine pancreatic phospholipase A2 complexed with micelles and a competitive inhibitor
The three-dimensional structure of porcine pancreatic PLA2 (PLA2), present in a 40 kDa ternary complex with micelles and a competitive inhibitor, has been determined using multidimensional heteronuclear NMR spect...