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Article

TP53 mutations predict disease control in metastatic colorectal cancer treated with cetuximab-based chemotherapy

Recent studies have suggested that activation of the EGFR pathway leads to malignant transformation only if the p53 protein is inactivated. Therefore, we evaluated the impact of TP53 mutations on cetuximab-based ...

A Oden-Gangloff, F Di Fiore, F Bibeau, A Lamy, G Bougeard… in British Journal of Cancer (2009)