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Chapter and Conference Paper
Conservative Surgery of the Mitral Valve: An Echocardiographic Long-Term Evaluation
Conservative surgery of the mitral valve is a very appealing procedure. In the last 3 years (1984–1987), 40 patients, aged 11 to 72 years (mean age of 46,33 years), underwent mitral repair in our department, a...
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Article
Cardiovascular autonomic dysfunction in normotensive awake subjects with obstructive sleep apnoea syndrome
Cardiovascular autonomic function in normotensive awake patients with obstructive sleep apnoea syndrome was studied in 21 normotensive (mean age 48 ± 14 years), drug-free men with obstructive sleep apnoea syndro...
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Article
Parallel increase in carotid, brachial and left ventricular cross-sectional areas in arterial hypertension
Few data have been published about the relation between the vessels geometry and development of left ventricular (LV) hypertrophy in patients with arterial hypertension. The aim of this study is to describe ar...
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Article
Cardiac autonomic modulation and incidence of late potentials in essential hypertension: role of age, sex, ventricular mass and remodeling
The influence of age, sex, left ventricular hypertrophy (LVH) and geometry on the autonomic activity to the heart was investigated in 96 hypertensive out-patients (53 men, mean age 53 ± 9 years) and 39 healthy...
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Article
Post-ejection thickening as a marker of viable myocardium. An echocardiographic study in patients with chronic coronary artery disease
The study aim was to assess whether post-ejection thickening (PT) is an useful marker of viable myocardium in patients with chronic coronary artery disease.
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Article
Cardiac autonomic tone during trandolapril-irbesartan low-dose combined therapy in hypertension: a pilot project
Pharmacological and clinical studies on the effects of angiotensin-converting enzyme (ACE) inhibitors support the idea of a central role played Angiotensin II which is able to cause cardiovascular and renal di...
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Article
Role of microRNAs in malignant mesothelioma
Malignant mesothelioma (MM) is an aggressive tumor, mainly derived from the pleura, which is predominantly associated with exposure to asbestos fibers. The prognosis of MM patients is particularly severe, with...
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Article
Open AccessSerum proteomic test in advanced non-squamous non-small cell lung cancer treated in first line with standard chemotherapy
VeriStrat is a blood-based proteomic test with predictive and prognostic significance in second-line treatments for non-small cell lung cancer (NSCLC). This trial was designed to investigate the role of VeriSt...
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Article
Open AccessThe role of CEA, CYFRA21-1 and NSE in monitoring tumor response to Nivolumab in advanced non-small cell lung cancer (NSCLC) patients
CEA, CYFRA21-1 and NSE are tumor markers used for monitoring the response to chemotherapy in advanced adenocarcinoma, squamous cell carcinoma and small-cell lung cancer, respectively. Their role in cancer immu...
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Article
Cardiovascular reflex tests detect autonomic dysfunction in symptomatic and pre-symptomatic subjects with hereditary transthyretin amyloidosis
Autonomic dysfunction is a distinctive but undervalued feature of hereditary transthyretin amyloidosis (ATTRv). It may predate the onset of polyneuropathy and cardiomyopathy, thereby providing crucial prognost...
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Article
Open AccessImproved overall survival in patients develo** endocrine toxicity during treatment with nivolumab for advanced non-small cell lung cancer in a prospective study
Immune checkpoint inhibitors (ICPIs) disrupting PD-1/PD-L1 axis have revolutionized the management of advanced non-small cell lung cancer (NSCLC). Some studies identified the development of endocrine toxicity ...
