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Article
Protumorigenic effects of mir-145 loss in malignant pleural mesothelioma
We identified a discrete number of microRNAs differentially expressed in benign or malignant mesothelial tissues. We focused on mir-145 whose levels were significantly downregulated in malignant mesothelial ti...
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Article
SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells
Here we show that pemetrexed-treated mesothelioma cells undergo accelerated senescence. This is characterized by the secretion of proinflammatory and mitogenic cytokines, reminiscent of an SASP (senescence-ass...