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  1. Article

    Open Access

    Targeting the radiation-induced ARv7-mediated circNHS/miR-512-5p/XRCC5 signaling with Quercetin increases prostate cancer radiosensitivity

    Radiation therapy (RT) with androgen deprivation therapy (ADT) is an effective therapy to suppress the locally advanced prostate cancer (PCa). However, we unexpectedly found that RT could also induce the andro...

    Dong Chen, Fu-Ju Chou, Yuhchyau Chen… in Journal of Experimental & Clinical Cancer … (2022)

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  2. Article

    Open Access

    ASC-J9® suppresses prostate cancer cell proliferation and invasion via altering the ATF3-PTK2 signaling

    Early studies indicated that ASC-J9®, an androgen receptor (AR) degradation enhancer, could suppress the prostate cancer (PCa) progression. Here we found ASC-J9® could also suppress the PCa progression via an ...

    Hao Tian, Fu-ju Chou, **g Tian, Yong Zhang… in Journal of Experimental & Clinical Cancer … (2021)

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  3. Article

    Open Access

    Estrogen receptor α in cancer associated fibroblasts suppresses prostate cancer invasion via reducing CCL5, IL6 and macrophage infiltration in the tumor microenvironment

    Cancer associated fibroblasts (CAF) play important roles in tumor growth that involves inflammation and epithelial cell differentiation. Early studies suggested that estrogen receptor alpha (ERα) was expressed...

    Chiuan-Ren Yeh, Spencer Slavin, Jun Da, Iawen Hsu, Jie Luo… in Molecular Cancer (2016)

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