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  1. Article

    Open Access

    Associations of Blood and Urinary Heavy Metals with Stress Urinary Incontinence Risk Among Adults in NHANES, 2003–2018

    People come into contact with heavy metals in various ways in their daily lives. Accumulating evidence shows that toxic metal exposure is hazardous to human health. However, limited information is available re...

    Maoling Fu, Zifan Zhu, Yechen **ang, Qiaoyue Yang… in Biological Trace Element Research (2024)

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  2. No Access

    Article

    Reactive Oxygen Species-Mediated Mitophagy and Cell Apoptosis are Involved in the Toxicity of Aluminum Chloride Exposure in GC-2spd

    Aluminum chloride is an inorganic polymeric coagulant commonly found in daily life and various materials. Although male reproductive toxicity has been associated with AlCl3 exposure, the underlying mechanism rema...

    Hui- xin Peng, Fu Chai, Ke-heng Chen, Yan-xin Huang… in Biological Trace Element Research (2024)

  3. No Access

    Article

    Selenium-Chitosan Protects Porcine Endometrial Epithelial Cells from Zearalenone-induced Apoptosis via the JNK/SAPK Signaling Pathway

    This study was designed to assess whether selenium-chitosan (Se-CTS) can protect porcine endometrial epithelial cells (PEECs) against damage and apoptosis induced by zearalenone (ZEA) via modulating the JNK/SA...

    Huanhuan Wang, Fuze She, Fu Chen, Kun Li, Shunyi Qin in Biological Trace Element Research (2024)

  4. No Access

    Article

    Proteomics Sequencing Reveals the Role of TGF-β Signaling Pathway in the Peripheral Blood of Offspring Rats Exposed to Fluoride

    The underlying mechanism of fluorosis has not been fully elucidated. The purpose of this study was to explore the mechanism of fluorosis induced by sodium fluoride (NaF) using proteomics. Six offspring rats ex...

    Fang-fang Yu, Shui-yuan Yu, Lei-zhen Duan, Shuo Yang… in Biological Trace Element Research (2024)

  5. No Access

    Article

    Dietary Iron Overload Triggers Hepatic Metabolic Disorders and Inflammation in Laying Hen

    Iron, an essential trace element, is involved in various physiological processes; however, consumption of excessive iron possesses detrimental effects. In practical feed production, the iron content added to f...

    Yue Li, Lan-**n Li, Han Cui, Wan-Xue Xu, Hong-Yu Fu… in Biological Trace Element Research (2024)

  6. No Access

    Article

    Effect of Germination on Mineral Content Changes in Brown Rice (Oryza sativa L.)

    Minerals are the essential micronutrients for human health. Brown rice is a whole-grain food rich in minerals, with its bran portion limiting the application of minerals. In the present study, the changes in t...

    **ang Li, Chunmin Ma, **n Bian, Yu Fu, Guang Zhang… in Biological Trace Element Research (2024)

  7. No Access

    Article

    Association of Magnesium, Iron, Copper, and Zinc Levels with the Prevalence of Behavior Problems in Children and Adolescents

    Magnesium (Mg), iron (Fe), copper (Cu), and zinc (Zn) are indispensable elements in children’s growth and development. However, epidemiological evidence regarding essential elements and their mixed exposure to...

    Ying Shen, Huyi **, Fanjia Guo, Wanting Zhang, Hao Fu… in Biological Trace Element Research (2024)

  8. No Access

    Article

    Human dental pulp stem cells have comparable abilities to umbilical cord mesenchymal stem/stromal cells in regulating inflammation and ameliorating hepatic fibrosis

    Hepatic fibrosis, also called cirrhosis, have wide prevalence worldwide for long yeas. Recently, many treatments for liver cirrhosis made marked progress, especially the umbilical cord-derived mesenchymal stro...

    Peixing Chen, Yanchun Lin, Wenbo Lin, Yun Li, Ting Fu, Yuanyue Liu, Tian Guan… in Human Cell (2024)

  9. Article

    Open Access

    Establishment and characterization of a novel hilar cholangiocarcinoma cell line, CBC3T-1

    Cholangiocarcinoma (CCA) is a group of malignant heterogeneous cancer arising from the biliary tree. The tumor is characterized by insidious onset, high degree of malignancy, poor prognosis, and high recurrenc...

    Mingzhen Bai, Ningzu Jiang, Wenkang Fu, Chongfei Huang, Liang Tian… in Human Cell (2024)

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  10. No Access

    Article

    A study on the effectiveness of sodium selenite in treating cadmium and perfluoro octane sulfonic (PFOS) poisoned zebrafish (Danio rerio)

    Perfluoro octane sulfonate (PFOS) and cadmium (Cd) are toxic elements in the environment. As a micronutrient trace element, selenium (Se) can mitigate the adverse effects induced by PFOS and Cd. However, few s...

    Wang Lu, Waqas Ahmed, Mohsin Mahmood, Ou Wenjie… in Biological Trace Element Research (2024)

  11. No Access

    Article

    Selenium-enriched Bacillus subtilis Improves Growth Performance, Antioxidant Capacity, Immune Status, and Gut Health of Broiler Chickens

    This study aimed to investigate the effects of selenium (Se)-enriched Bacillus subtilis (Se-BS) on growth performance, antioxidant capacity, immune status, and gut health in broilers. A total of 240 one-day-old A...

    Huiling Qiu, Shansong Gao, Lele Hou, An** Li… in Biological Trace Element Research (2023)

  12. No Access

    Article

    Acute Aluminum Sulfate Triggers Inflammation and Oxidative Stress, Inducing Tissue Damage in the Kidney of the Chick

    In this study, a total of 20 7-day-old chicks were randomly divided into an experimental group and a control group. The experimental group was administered aluminum sulfate (Al2(SO4)3) once by gavage, and the con...

    Bo Chen, Lina Chen, Zhiqing Yang, Qiang Fu, **nran Li… in Biological Trace Element Research (2023)

  13. No Access

    Article

    Selenium Deficiency Caused Fibrosis as an Oxidative Stress-induced Inflammatory Injury in the Lungs of Mice

    Selenium (Se) is a vital trace element in the regulation of inflammation and antioxidant reactions in both animals and humans. Se deficiency is rapidly affecting lung function. The present study investigated t...

    Yu-xin Fu, Yi-bo Wang, Qing-wei Bu, Meng-yao Guo in Biological Trace Element Research (2023)

  14. No Access

    Article

    Zinc supplementation ameliorates sorafenib-induced cognitive impairment through ROS/JNK signaling pathway

    Sorafenib, a multiple kinase inhibitor, is widely used in cancer patients. Recently, clinical studies highlighted the relationship between cognitive deficits and sorafenib exposure. Zinc abundant in the body h...

    Can-Can Zhou, Yu-Qiong He, Yu-Shuang Qiu, Chen-Xu Ni… in Biological Trace Element Research (2023)

  15. No Access

    Article

    METTL3 promotes m6A hypermethylation of RBM14 via YTHDF1 leading to the progression of hepatocellular carcinoma

    Liver is a well-known immunological organ with unique microenvironment. In normal conditions, the rich immune-infiltrating cells cooperate with non-parenchymal cells, such as Kupffer cells (KCs). The presence ...

    **gyao Hu, Liang Yang, Xueqiang Peng, Minghuan Mao, **aodan Liu, Jianbo Song… in Human Cell (2022)

  16. No Access

    Article

    The Role of PTEN/PI3K/AKT Signaling Pathway in Apoptosis of Liver Cells in Cocks with Manganese Toxicity

    PTEN/PI3K/AKT signaling pathway is an important pathway for cell proliferation and apoptosis. Exposure to excess manganese (Mn) can cause damage in organisms. However, whether Mn toxicity can cause apoptosis i...

    Liu **aofei, Hou Yan, Fu Yu, Fan **g, Yangyang… in Biological Trace Element Research (2022)

  17. No Access

    Article

    Zinc Deficiency Aggravates Oxidative Stress Leading to Inflammation and Fibrosis in Lung of Mice

    Zinc (Zn) is an essential trace element for the body. Studies have confirmed that Zn deficiency can cause oxidative stress. The purpose of the present study was designed to investigate the effect of Zn on fibr...

    Qirui Zhang, Yao Xue, Yuxin Fu, Bowen Bao… in Biological Trace Element Research (2022)

  18. No Access

    Article

    Circular RNA circPBX3 promotes cisplatin resistance of ovarian cancer cells via interacting with IGF2BP2 to stabilize ATP7A mRNA expression

    Circular RNAs (circRNAs) are a class of non-coding RNAs with a unique covalently closed loop structure. Recent studies indicate that dysregulation of circRNAs acts a role in cancer progression and chemotherapy...

    Lihua Fu, Dan Zhang, Nuo Yi, Yanjun Cao, Yaxian Wei, Wen**g Wang, Li Li in Human Cell (2022)

  19. No Access

    Article

    Lead Exposure in Developmental Ages Promotes Aβ Accumulation by Disturbing Aβ Transportation in Blood-Cerebrospinal Fluid Barrier/Blood–Brain Barriers and Impairing Aβ Clearance in the Liver

    Environmental lead exposure is closely related to the progression of Alzheimer’s disease (AD). Our previous study has shown that exposure to lead could result in the cholesterol unbalance and increase amyloid-...

    Can-Can Zhou, Xu-Jie Wang, Zi-Chen Li, Wen-Jie Lu… in Biological Trace Element Research (2022)

  20. No Access

    Article

    Selenide Chitosan Sulfate Improved the Hepatocyte Activity, Growth Performance, and Anti-oxidation Capacity by Activating the Thioredoxin Reductase of Chickens In Vitro and In Vivo

    Chicken hepatocytes were cultured in vitro and 240 specific pathogen-free (SPF) white leghorns chickens (7 days old) were obtained. The hepatocytes and chickens were randomly allocated to one of six treatment ...

    Lele Hou, Huiling Qiu, Lianqin Zhu, Shansong Gao… in Biological Trace Element Research (2022)

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