28 Result(s)
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Article
Suppression of growth of highly-metastatic human breast cancer cells by norcantharidin and its mechanisms of action
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Article
Effects of theanine on growth of human lung cancer and leukemia cells as well as migration and invasion of human lung cancer cells
The aim of this study is to investigate the effects of theanine, a tea characteristic amino acid, on human lung cancer and leukemia cells. In the present study, we have demonstrated that theanine suppressed th...
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Article
Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-κB signaling
Matrine has shown therapeutic and/or adjuvant therapeutic effects on the treatment of some patients with breast cancer. However, its mechanisms of action are largely unknown. To disclose the mechanisms, we inv...
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Article
Suppression of growth of highly-metastatic human breast cancer cells by norcantharidin and its mechanisms of action
The effects of norcantharidin (NCTD) on the growth of highly-metastatic human breast cancer cells were investigated by in vitro and ex vivo assays. Our results indicated that norcantharidin inhibited the in vi...
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Article
Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration
The purpose of this study is to investigate in vitro and ex vivo effects of matrine on the growth of human lung cancer and hepatoma cells and the cancer cell migration as well as the expressions of related pro...
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Article
Establishment and biological characteristics of Ujumqin sheep fibroblast line
A Ujumqin sheep ear marginal tissue (USEM) fibroblast line, frozen in 147 cryovials with 4 × 106 cell each, was successfully established from 33 Ujumqin sheep ear marginal tissues using explant culture and cryopr...
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Article
Inhibitory effects of norcantharidin against human lung cancer cell growth and migration
The effects of norcantharidin (NCTD), an anticancer drug in China, on the growth and migration in human lung cancer cells were investigated by in vitro and ex vivo assays. NCTD significantly inhibited the in v...
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Article
Suppression of human lung cancer cell growth and migration by berbamine
The purpose of this study is to investigate the effects of berbamine (BER), a naturally occurring small-molecule compound from Traditional Chinese Medicine (TCM) Berberis amurensis, on the growth and migration of...
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Article
On-line monitoring of oxygen in Tubespin, a novel, small-scale disposable bioreactor
A novel, optical sensor was fixed in a new type of disposable bioreactor, Tubespin, for the on-line (real-time) monitoring of dissolved oxygen concentrations during cell culture. The cell density, viability an...
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Article
Establishment, characterization and immortalization of a fibroblast cell line from the Chinese red belly toad Bombina maxima skin
The skin of the amphibian Bombina maxima is rich in biologically active proteins and peptides, most of which have mammalian analogues. The physiological functions of most of the mammalian analogues are still unkn...
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Article
A rapid fluorescent screening method for cellular sensitivity to anti-cancer compound
The tetrazolium salts (MTT, XTT, MTS, WST) based colorimetric assay or resazurin based fluorimetric assay are currently typical methods for cell sensitivity determination to anticancer compounds. We presented ...
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Article
VEGF165 expressing bone marrow mesenchymal stem cells differentiate into hepatocytes under HGF and EGF induction in vitro
A short half-life and low levels of growth factors in an injured microenvironment necessitates the sustainable delivery of growth factors and stem cells to augment the regeneration of injured tissues. Our aim ...
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Article
RETRACTED ARTICLE: Lupeol induces apoptosis and inhibits invasion in gallbladder carcinoma GBC-SD cells by suppression of EGFR/MMP-9 signaling pathway
The cytostatic drug from fruits and other plant derived products have acted as a chemotherapeutic agent used in treatment of a wide variety of cancers. Lupeol, a dietary triterpene, present in many fruits and ...
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Article
Fluorescent labeling for clonal selection of Marc 145 cells secreting high levels of recombinant protein PBD-1
Despite the powerful impact gene expression markers like the green fluorescent protein (GFP) or enhanced GFP (EGFP) exert on linking the expression of recombinant protein for selection of high producers in rec...
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Article
Atoh7 promotes retinal Müller cell differentiation into retinal ganglion cells
Glaucoma is one of the leading eye diseases due to the death of retinal ganglion cells. Increasing evidence suggests that retinal Müller cells exhibit the characteristics of retinal progenitor cells and can di...
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Article
Osteoprotegerin exposure at different stages of osteoclastogenesis differentially affects osteoclast formation and function
This study aimed to investigate the effects of osteoprotegerin (OPG), a decoy receptor for receptor activator for nuclear factor κB ligand (RANKL), during the various stages of osteoclast differentiation, and ...
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Article
Development and characterization of monoclonal antibody against human IL-37b
IL-37 has been described as a natural inhibitor of immune responses. Monoclonal antibody (mAb) against human IL-37b with high affinity and specificity can serve as a molecular probe to detect IL-37 and study I...
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Article
Analysis of toxicity effects of Di-(2-ethylhexyl) phthalate exposure on human bronchial epithelial 16HBE cells
Recent studies have indicated that Di-(2-ethylhexyl) phthalate (DEHP), the most commonly used plasticizer in daily-life products, could be dispersed in indoor air and induce human exposure via inhalation. DEHP...
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Article
Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway
Oxymatrine extracted from Sophora flavescens Ait as a natural polyphenolic phytochemical has been demonstrated to exhibit anti-tumor effects on various cancers, including Gallbladder carcinoma (GBC). However, ...
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Article
Glioma targeting peptide in combination with the P53 C terminus inhibits glioma cell proliferation in vitro
Glioma is a prevalent malignant primary brain tumor in adults, the treatment for which remains a challenge due to its high infiltration and recurrence. Hence, treatments that lead to the suppression of glioma ...
