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  1. No Access

    Article

    Functional redundancy of two transcriptional coactivator complexes

    Helen C. Causton, Tong Ihn Lee, Frank C.P. Holstege, Ezra Jennings in Nature Genetics (1999)

  2. Article

    Combinatorial negative regulation of glucose-responsive genes in yeast

    Ezra G. Jennings, Frank C.P. Holstege, John J. Wyrick, Richard A. Young in Nature Genetics (1999)

  3. No Access

    Article

    Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

    Microarray analysis has become a widely used tool for the generation of gene expression data on a genomic scale. Although many significant results have been derived from microarray studies, one limitation has ...

    Alvis Brazma, Pascal Hingamp, John Quackenbush, Gavin Sherlock in Nature Genetics (2001)

  4. No Access

    Article

    An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas

    Metastasis is the process by which cancers spread to distinct sites in the body. It is the principal cause of death in individuals suffering from cancer. For some types of cancer, early detection of metastasis...

    Paul Roepman, Lodewyk F A Wessels, Nienke Kettelarij, Patrick Kemmeren in Nature Genetics (2005)

  5. Article

    Open Access

    Identification and characterization of relapse-initiating cells in MLL-rearranged infant ALL by single-cell transcriptomics

    Infants with MLL-rearranged infant acute lymphoblastic leukemia (MLL-r iALL) undergo intense therapy to counter a highly aggressive malignancy with survival rates of only 30–40%. The majority of patients initiall...

    Tito Candelli, Pauline Schneider, Patricia Garrido Castro, Luke A. Jones in Leukemia (2022)

  6. Article

    Open Access

    Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS

    Gene fusions are important cancer drivers in pediatric cancer and their accurate detection is essential for diagnosis and treatment. Clinical decision-making requires high confidence and precision of detection...

    Ianthe A. E. M. van Belzen, Casey Cai, Marc van Tuil, Shashi Badloe in BMC Cancer (2023)