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Article
Mechanistics of formation and ultrastructural evaluation of hepatocyte spheroids
Freshly harvested rat hepatocytes form spheroids on uncoated positively charged polystyrene surfaces. Time lapse microscopy revealed that cell movement and reorganization were involved in spheroid formation. U...
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Article
Extended liver-specific functions of porcine hepatocyte spheroids entrapped in collagen gel
The potential use of porcine hepatocytes in a bioartificial liver device requires large quantities of viable and highly active cells. To facilitate the scaling up of the system, liver specific activities of he...