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Article
Cerebrospinal fluid levels of Aβ42 relationship with cholinergic cortical activity in Alzheimer’s disease patients
The dysfunction of cholinergic neurons is a typical hallmark in Alzheimer’s disease (AD). In animal models of AD, fragments of amyloid beta protein (Aβ) and Tau protein are thought to interfere with central ch...
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Article
Dopaminergic Modulation of Cortical Plasticity in Alzheimer’s Disease Patients
In animal models of Alzheimer’s disease (AD), mechanisms of cortical plasticity such as long-term potentiation (LTP) and long-term depression (LTD) are impaired. In AD patients, LTP-like cortical plasticity is...
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Chapter
Congenital Anomalies of the External Male Genitalia
The chapter is aimed at describing the main congenital disorders of the external male genitalia (penis, scrotum, and testis) in order to enable the reader to promptly recognize such malformations in the newbor...
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Article
Urinary schistosomiasis in migrant population: a case series from a single centre in southern Italy
To understand the frequency of urinary schistosomiasis, in migrants in clinical follow-up at the infectious disease outpatient clinic of ARNAS Civico Hospital in Palermo Italy, to raise awareness on this negle...
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Article
Suboptimal performance of APRI and FIB-4 in ruling out significant fibrosis and confirming cirrhosis in HIV/HCV co-infected and HCV mono-infected patients
We aimed to assess the diagnostic reliability of two indirect biomarkers, APRI and FIB-4, for the staging of liver fibrosis using transient elastography (TE) as reference standard, among HIV/HCV co-infected an...
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Article
Endovascular therapy for acute ischemic stroke: which role for neurologists?
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Article
Introduction to the Italian section for young neurologists
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Article
Dementia care and COVID-19 pandemic: a necessary digital revolution
Due to the COVID-19 pandemic, most memory clinics have had to suspend their activities. On the other hand, international dementia experts have recommended to provide urgently worldwide support for people livin...
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Article
Open AccessCOVID-19 and neurological training in Europe: from early challenges to future perspectives
The worldwide SARS-CoV-2 pandemic is dramatically affecting health systems with consequences also for neurological residency training. Here we report early experiences and challenges that European neurologists...
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Article
COVID-19 impact on neurology training program in Italy
The ongoing COVID-19 pandemic is having a huge impact on clinical activity of all hospitals, including the ones involved in training of residents. In addition, neurology residents underwent substantial modific...
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Article
Open AccessTelemedicine application to headache: a critical review
Migraine affects more than a billion people all over the world and requires critical employment of healthcare resources. Telemedicine could be a reasonable tool to manage people suffering from headaches, and i...
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Article
The future of neurology after the COVID-19 pandemic according to neurology residents
The ongoing COVID-19 pandemic has resulted in significant changes in the delivery of neurological disease care and in neurology training in academic departments.
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Article
Open AccessInterleukin-1 receptor associated kinase 2 is a functional downstream regulator of complement factor D that controls mitochondrial fitness in diabetic cardiomyopathy
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Article
Open AccessA new perspective on positive symptoms: expression of damage or self-defence mechanism of the brain?
Usually, positive neurological symptoms are considered as the consequence of a mere, afinalistic and abnormal increase in function of specific brain areas. However, according to the Theory of Active Inference,...
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Article
Is blood pTau a reliable indicator of the CSF status? A narrative review
The identification of biomarkers for the early diagnosis of Alzheimer’s disease (AD) is a crucial goal of the current research. Blood biomarkers are less invasive, easier to obtain and achievable by a cheaper ...