Skip to main content

10 Result(s)

within Florence Demenais Remove this filter Biomedicine, general Remove this filter

and

  1. No Access

    Article

    Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

    Most genetic susceptibility to cutaneous melanoma remains to be discovered. Meta-analysis genome-wide association study (GWAS) of 36,760 cases of melanoma (67% newly genotyped) and 375,188 controls identified ...

    Maria Teresa Landi, D. Timothy Bishop, Stuart MacGregor… in Nature Genetics (2020)

  2. No Access

    Article

    Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

    We examined common variation in asthma risk by conducting a meta-analysis of worldwide asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of individuals from ethnically diverse popu...

    Florence Demenais, Patricia Margaritte-Jeannin, Kathleen C. Barnes… in Nature Genetics (2018)

  3. No Access

    Article

    Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma

    Matthew Law, Mark Iles and colleagues report the results of a large-scale genome-wide meta-analysis of cutaneous malignant melanoma. They confirm previously reported association signals and identify five new s...

    Matthew H Law, D Timothy Bishop, Jeffrey E Lee, Myriam Brossard… in Nature Genetics (2015)

  4. No Access

    Article

    Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma

    Maria Teresa Landi and colleagues identify a rare missense variant in POT1 shared by five melanoma-prone families from Italy and associated with increased telomere length and telomere fragility. They also identif...

    Jianxin Shi, **aohong R Yang, Bari Ballew, Melissa Rotunno… in Nature Genetics (2014)

  5. No Access

    Article

    Genome-wide association study identifies three new melanoma susceptibility loci

    Timothy Bishop and colleagues of the GenoMEL Consortium report a genome-wide association study for melanoma, identifying three new susceptibility loci.

    Jennifer H Barrett, Mark M Iles, Mark Harland, John C Taylor… in Nature Genetics (2011)

  6. No Access

    Article

    Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3

    Stuart MacGregor and colleagues report the results of a genome-wide association study for melanoma susceptibility in an Australian population. They identify a new melanoma susceptibility locus on chromosome 1.

    Stuart MacGregor, Grant W Montgomery, Jimmy Z Liu, Zhen Zhen Zhao… in Nature Genetics (2011)

  7. No Access

    Article

    Genome-wide association study identifies three loci associated with melanoma risk

    Timothy Bishop and colleagues from GenoMEL present a genome-wide association study for melanoma. They report three loci associated with susceptibility to melanoma, of which two were previously associated with ...

    D Timothy Bishop, Florence Demenais, Mark M Iles, Mark Harland… in Nature Genetics (2009)

  8. No Access

    Article

    Common sequence variants on 20q11.22 confer melanoma susceptibility

    Brown et al. report results of a genome-wide association study for melanoma. Their screen, which used a pooling strategy, identified common variants on 20q11.22 associated with melanoma susceptibility. In two sep...

    Kevin M Brown, Stuart MacGregor, Grant W Montgomery, David W Craig… in Nature Genetics (2008)

  9. Article

    Open Access

    A two-step multiple-marker strategy for genome-wide association studies

    Genome-wide association studies raise study-design and analytical issues that are still being debated. Among them, stands the issue of reducing the number of markers to be genotyped without loss of efficiency ...

    Hugues Aschard, Mickaël Guedj, Florence Demenais in BMC Proceedings (2007)

    Download PDF (389 KB) View Article

  10. No Access

    Article

    Dissecting the loci controlling fetal haemoglobin production on chromosomes 11p and 6q by the regressive approach

    The Changes in the type of haemoglobin (Hb) produced during embryonic, fetal and adult life, have served as a paradigm for understanding the developmental regulation of human genes. A genetically determined pe...

    Jamie E. Craig, Jacques Rochette, Chris A. Fisher, David J. Weatherall… in Nature Genetics (1996)