719 Result(s)
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Article
Open AccessTemporal relationship between hepatic steatosis and fasting blood glucose elevation: a longitudinal analysis from China and UK
The link between nonalcoholic fatty liver disease and type 2 diabetes has not been fully established. We investigated the temporal relationship between nonalcoholic fatty liver disease (NAFLD) and type 2 diabe...
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Article
Resolution of anti-LGI1-associated autoimmune encephalitis in a patient after treatment with efgartigimod
Anti leucine-rich, glioma inactivated 1 (LGI1) antibody-associated autoimmune encephalitis (AE) is the second most common AE, where the trafficking and recycling of the pathogenic immunoglobulin (IgG) can be c...
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Open AccessSleep disorder experienced by healthcare nurses after terminating Zero-COVID-19 policy
Medical staff, especially nurses, suffered great anxiety and stress from the COVID-19 pandemic, which negatively affected their sleep quality. In this study, we aimed to analyze the sleep quality of nursing st...
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Open AccessAlternate levels versus all levels mini-plate fixation in C3-6 cervical laminoplasty: a retrospective comparative study
The purpose of this study is to compare radiological and clinical outcomes between alternate levels (C4 and C6) and all levels mini-plate fixation in C3-6 unilateral open-door laminoplasty.
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Article
Cross-sectional study of hepatitis B virus infection in female breast cancer patients in China for the first time diagnosed
The correlation between breast cancer and hepatitis B virus (HBV) remains inconclusive. This study aims to explore the serological status of HBV infection and past infection in different age groups of female b...
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Open AccessA Phase 3, Randomized, Controlled Trial Evaluating the Efficacy and Safety of Ropeginterferon Alfa-2b in Patients with Moderate COVID-19
Ropeginterferon alfa-2b is a novel mono-pegylated proline-interferon. This clinical study aimed to evaluate its antiviral efficacy of ropeginterferon alfa-2b against SARS-CoV-2 infection.
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Article
Effects of different treatment modalities on cardiovascular disease in ARR-positive hypertensive patients
Data on the prognosis of clinically undiagnosed hypertensive patients who are aldosterone-to-renin ratio (ARR) positive are still scarce. Therefore, we investigated the clinical characteristics of clinically u...
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Article
ACSF2 and lysine lactylation contribute to renal tubule injury in diabetes
Lactate accumulation is reported to be a biomarker for diabetic nephropathy progression. Lactate drives lysine lactylation, a newly discovered post-translational modification that is involved in the pathogenes...
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Article
Open AccessDiagnostic Value of 99mTc-MIBI Myocardial Perfusion Imaging in Detecting Myocardial Ischemia of Children with Kawasaki Disease and Coronary Artery Lesions
Pediatric patients with coronary artery lesions (CALs) after Kawasaki disease (KD) may be complicated with myocardial ischemia. Although previous studies in adults have proven the diagnostic value of 99mTc-MIBI m...
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Article
Effectiveness of Lianhua Qingwen Granule and **gyin Gubiao Prescription in Omicron BA.2 Infection and Hospitalization: A Real-World Study of 56,244 Cases in Shanghai, China
To examine the effectiveness of Chinese medicine (CM) Lianhua Qingwen Granule (LHQW) and **gyin Gubiao Prescription (JYGB) in asymptomatic or mild patients with Omicron infection in the shelter hospital.
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Article
Comparison of totally robotic and totally laparoscopic gastrectomy for gastric cancer: a propensity score matching analysis
With the improvements in laparoscopic or robotic surgical techniques and instruments, a growing number of surgeons have attempted to complete all digestive tract reconstruction intracorporeally; these procedur...
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Open AccessThe molecular signature and prognosis of glioma with preoperative intratumoral hemorrhage: a retrospective cohort analysis
Intratumoral hemorrhage, though less common, could be the first clinical manifestation of glioma and is detectable via MRI; however, its exact impacts on patient outcomes remain unclear and controversial. The ...
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Open AccessEffect of duloxetine on changes in serum proinflammatory cytokine levels in patients with major depressive disorder
Accumulating evidence supports the idea that inflammation may contribute to the pathophysiology of major depressive disorder (MDD). Duloxetine, a serotonin-norepinephrine reuptake inhibitor, exhibits anti-infl...
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Article
Air pollution, greenspace exposure and risk of Parkinson's disease: a prospective study of 441,462 participants
The current understandings of the relationship between air pollution (AP), greenspace exposure and Parkinson's Disease (PD) remain inconclusive.
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Correction to: Safety and immunogenicity of SARS-CoV-2 vaccines in Chinese patients with cirrhosis: a prospective multicenter study
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Article
Open AccessConstructing and Validating a Nomogram Model for Short-Term Prognosis of Patients with AChR-Ab+ GMG
This study aimed to establish and validate a nomogram prognostic model for predicting short-term efficacy of acetylcholine receptor antibody-positive (AChR-Ab+) generalized myasthenia gravis (GMG).
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Article
Prognostic performance of MRI LI-RADS version 2018 features and clinical-pathological factors in alpha-fetoprotein-negative hepatocellular carcinoma
To evaluate the role of the magnetic resonance imaging (MRI) Liver Imaging Reporting and Data System (LI-RADS) version 2018 features and clinical-pathological factors for predicting the prognosis of alpha-feto...
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Open AccessElectroacupuncture and carbamazepine for patients with trigeminal neuralgia: a randomized, controlled, 2 × 2 factorial trial
Trigeminal neuralgia (TN) is difficult to treat due to its severe pain intensity and recurring episodes, which significantly impact quality of life.
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Article
Open AccessEnd-organ damage from neonatal invasive fungal infection: a 14-year retrospective study from a tertiary center in China
Invasive fungal infection (IFI) has become an increasing problem in NICU neonates, and end-organ damage (EOD) from IFI is one of the leading causes of morbidity and mortality in neonates. This study was conduc...
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Article
Automatic planning of maxillary anterior dental implant based on prosthetically guided and pose evaluation indicator
Preoperative planning of maxillary anterior dental implant is a prerequisite to ensuring that the implant achieves the proper three-dimensional (3D) pose, which is essential for its long-term stability. Howeve...
