56 Result(s)
within
Feng Jiang**
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessB-cell hub genes play a cardiovascular pathogenic role of in childhood obesity and Kawasaki disease as revealed by transcriptomics-based analyses
The study aims to explore the central genes that Kawasaki disease (KD) and Obesity (OB) may jointly contribute to coronary artery disease. Investigating single-cell datasets (GSE168732 and GSE163830) from a co...
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Open AccessPerspectives on policing education and careers: insights from undergraduate students of China’s police academies
This study delves into the perspectives of Chinese police academy undergraduate students concerning their education and career paths within police academies. Employing a qualitative research design, in-depth i...
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Open AccessRevealing brain cell-stratified causality through dissecting causal variants according to their cell-type-specific effects on gene expression
The human brain has been implicated in the pathogenesis of several complex diseases. Taking advantage of single-cell techniques, genome-wide association studies (GWAS) have taken it a step further and revealed...
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Open AccessFerritinophagy mediates adaptive resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer
Osimertinib (Osi) is a widely used epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). However, the emergence of resistance is inevitable, partly due to the gradual evolution of adaptive res...
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Article
Open AccessAssessing causal relationships between gut microbiota and psoriasis: evidence from two sample Mendelian randomization analysis
Mounting data hints that the gut microbiota's role may be pivotal in understanding the emergence of psoriasis. However, discerning a direct causal link is yet elusive. In this exploration, we adopted a Mendeli...
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Open AccessShear damage mechanisms of jointed rock mass: a macroscopic and mesoscopic study
The joints are existing throughout the underground rock mass. It is of great significance to investigate the shear performance of the rock mass to maintain the stability of the underground structure. In this s...
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Open AccessA rapid evaluation method of blasting effect based on optimized image segmentation algorithm and application in engineering
To quickly determine the blasting block degree and conduct an accurate and objective analysis of the tunnel blasting effect, this study has enhanced and improved upon the traditional genetic algorithm and Otsu...
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Open AccessA landscape of gene expression regulation for synovium in arthritis
The synovium is an important component of any synovial joint and is the major target tissue of inflammatory arthritis. However, the multi-omics landscape of synovium required for functional inference is absent...
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Open AccessResearch on the deformation laws of buildings adjacent to shield tunnels in clay strata
Earth pressure shields are widely used in tunnel construction due to their low environmental impact and mechanized operations. However, ensuring the stability of the excavation surface during the construction ...
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Open AccessA dose-escalation study of HP501, a highly selective URAT1 inhibitor, in male Chinese patients with hyperuricemia
HP501 is a highly selective renal urate transporter 1 (URAT1) inhibitor used for treating hyperuricemia. This study aimed to evaluate the tolerability, pharmacokinetics, and pharmacodynamics of HP501 in male C...
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Article
Open AccessSecondary structures that regulate mRNA translation provide insights for ASO-mediated modulation of cardiac hypertrophy
Translation of upstream open reading frames (uORFs) typically abrogates translation of main (m)ORFs. The molecular mechanism of uORF regulation in cells is not well understood. Here, we data-mined human and mo...
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Article
Open AccessResearch on electromagnetic characteristics of traction motor rotary shafts with variable parameter defects based on finite element method
In view of the breakage of the rotary shaft of the traction motor of the locomotive, in order to ensure the reliability and safety of the equipment, this paper studies the magnetic field containing rich inform...
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Open AccessLove and affectionate touch toward romantic partners all over the world
Touch is the primary way people communicate intimacy in romantic relationships, and affectionate touch behaviors such as stroking, hugging and kissing are universally observed in partnerships all over the worl...
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Open AccessSelf-organized hetero-nanodomains actuating super Li+ conduction in glass ceramics
Easy-to-manufacture Li2S-P2S5 glass ceramics are the key to large-scale all-solid-state lithium batteries from an industrial point of view, while their commercialization is greatly hampered by the low room temper...
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Article
Open AccessModernization, collectivism, and gender equality predict love experiences in 45 countries
Recent cross-cultural and neuro-hormonal investigations have suggested that love is a near universal phenomenon that has a biological background. Therefore, the remaining important question is not whether love...
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Article
Open AccessGPSM1 impairs metabolic homeostasis by controlling a pro-inflammatory pathway in macrophages
G-protein-signaling modulator 1 (GPSM1) exhibits strong genetic association with Type 2 diabetes (T2D) and Body Mass Index in population studies. However, how GPSM1 carries out such control and in which types of ...
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Article
Open AccessIon rectification based on gel polymer electrolyte ionic diode
Biological ion channels rely on ions as charge carriers and unidirectional ion flow to produce and transmit signals. To realize artificial biological inspired circuitry and seamless human-machine communication...
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Open AccessBond engineering of molecular ferroelectrics renders soft and high-performance piezoelectric energy harvesting materials
Piezoelectric materials convert mechanical stress to electrical energy and thus are widely used in energy harvesting and wearable devices. However, in the piezoelectric family, there are two pairs of propertie...
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Open AccessResearch on recognition method of leaf diseases of woody fruit plants based on transfer learning
Fruit leaf diseases have a significant impact on the later development and maturity of fruits, so rapid and accurate identification of fruit leaf diseases plays an important role in the development of fruit pr...
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Open AccessEffect of distributed Bragg reflectors on photoluminescence properties of CH3NH3PbI3 film
The nanoporous (NP) GaN distributed Bragg reflector (DBR) was prepared by using electrochemical etching. Then the NP-GaN DBR was pretreated by using ozone treatment. Atomic force microscopy and X-ray diffracti...
