626 Result(s)
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A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human health, causing pandemics with high mortality and pathogenicity. Given the emergence of increasingly drug-resistant str...
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Open AccessB-cell hub genes play a cardiovascular pathogenic role of in childhood obesity and Kawasaki disease as revealed by transcriptomics-based analyses
The study aims to explore the central genes that Kawasaki disease (KD) and Obesity (OB) may jointly contribute to coronary artery disease. Investigating single-cell datasets (GSE168732 and GSE163830) from a co...
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Thermoelectric transport properties of p-type Bi2Se3–Sb2Se3–In2Se3 high entropy compounds
The introduction of entropy concept into thermoelectric materials recently has attracted broad interest. Herein, we showed the phase diagram of the ternary systems of Bi2Se3–Sb2Se3–In2Se3. Among the high entropy ...
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The non-traditional and multi-energy field hybrid machining processes of cemented carbide: a comprehensive review
Cemented carbide has been widely applied in the manufacturing industry due to the excellent wear resistance and corrosion resistance. As a typical difficult-to-machine material, it faces many challenges such a...
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Open AccessPerspectives on policing education and careers: insights from undergraduate students of China’s police academies
This study delves into the perspectives of Chinese police academy undergraduate students concerning their education and career paths within police academies. Employing a qualitative research design, in-depth i...
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Open AccessEffects of super-enhancers in cancer metastasis: mechanisms and therapeutic targets
Metastasis remains the principal cause of cancer-related lethality despite advancements in cancer treatment. Dysfunctional epigenetic alterations are crucial in the metastatic cascade. Among these, super-enhan...
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Open AccessRevealing brain cell-stratified causality through dissecting causal variants according to their cell-type-specific effects on gene expression
The human brain has been implicated in the pathogenesis of several complex diseases. Taking advantage of single-cell techniques, genome-wide association studies (GWAS) have taken it a step further and revealed...
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Open AccessApplication of modified Yamane technique in intrascleral intraocular lens fixation combined with or without iris reconstruction
To explore the application and long-term clinical effects of modified Yamane technique in intrascleral intraocular lens (IOL) fixation combined with or without iris reconstruction.
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Article
Identification of individual plants carrying viruses or a viroid in Pyrus betulifolia seedlings and virus-tested pear mother plants by group testing
Monitoring the sanitary status of a large population of vegetative propagation materials is a challenge because it requires expensive and time-consuming testing. Here we report a group testing strategy to iden...
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Retraction Note: Medical image semantic segmentation based on deep learning
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The influence of workplace friendship on job crafting: based on affective events theory
With the continuous development of Internet technology and digital economy, the external environment is constantly impacting the nature of work and existing work structures, making work highly ambiguous, dynam...
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Effect of silica on crystallization process of calcium ferrite: thermodynamic and kinetic analysis
SiO2 is the main component of gangue in sinters and a crucial constituent in the formation of the SiO2–Fe2O3–CaO (SFC) system. The non-isothermal crystallization kinetics of the SFC system were investigated using...
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Reducing Data Transmission Efficiency in Wireless Capsule Endoscopy through DL-CEndo Framework: Reconstructing Lossy Low-Resolution Luma Images and Improving Summarization
Wireless Capsule Endoscopy (WCE) is the preferred technology for the diagnosis and evaluation of small bowel disorders. The concluding WCE video comprises as many as 150,000 images. Within this extensive colle...
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Effect of Pre-strain on Microstructure and Corrosion Behavior of a Novel High-Zn Containing Al-Zn-Mg-Cu Alloy
The effect of pre-strain on microstructure, mechanical property and corrosion behavior of a novel high-Zn containing Al-Zn-Mg-Cu alloy was investigated by the means of x-ray diffraction, electron back-scattere...
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Article
Open AccessFerritinophagy mediates adaptive resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer
Osimertinib (Osi) is a widely used epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). However, the emergence of resistance is inevitable, partly due to the gradual evolution of adaptive res...
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Different ENSO Impacts on Eastern China Precipitation Patterns in Early and Late Winter Associated with Seasonally-Varying Kuroshio Anticyclonic Anomalies
Winter precipitation over eastern China displays remarkable interannual variability, which has been suggested to be closely related to El Niño–Southern Oscillation (ENSO). This study finds that ENSO impacts on...
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Open AccessStable carbon isotope composition and intrinsic water use efficiency in plants along an altitudinal gradient on the eastern slope of Yulong Snow Mountain, China
Stable carbon isotope composition (δ13Cp) can be used to estimate the changes in intrinsic water use efficiency (iWUE) in plants, which helps us to better understand plants’ response strategies to climate change....
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Experimental investigation on the mechanical behavior and fracture mechanism of sandstone after heat treatment
Rocks extracted from deep mining operations often undergo various complex temperature and dynamic load disturbances. In order to investigate the influence of temperature on the mechanical characteristics and f...
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Hot Deformation Behavior and Microstructure Evolution of a Novel High-Zn Containing Al-Zn-Mg-Cu-Zr Alloy
The hot deformation behavior of a novel high-Zn containing Al-Zn-Mg-Cu-Zr alloy was investigated by isothermal compression tests under the conditions of 350-500 °C and 0.0001-10 s−1. Arrhenius constitutive model ...
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Facile synthesis, characterization, biocompatibility and protein loading/release property of zinc-doped hollow mesoporous bioactive glass nanospheres
We synthetized hollow mesoporous bioactive glass nanospheres (HMBGS) and zinc-doped hollow mesoporous bioactive glass nanospheres (Zn-HMBGS) in which 5 mol% zinc was substituted for calcium using polyacrylic a...