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    Article

    Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice

    Autism spectrum disorders (ASDs) are four times more common in males than in females, but the underlying mechanisms are poorly understood. We characterized sexually dimorphic changes in mice carrying a heteroz...

    Hwa** Jung, Haram Park, Yeonsoo Choi, Hyo** Kang, Eunee Lee… in Nature Neuroscience (2018)

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    Article

    Social deficits in IRSp53 mutant mice improved by NMDAR and mGluR5 suppression

    Enhanced NMDA receptor function and social interaction deficits are observed in mice lacking the excitatory postsynaptic scaffolding protein IRSp53. Reducing NMDAR activity by pharmacological methods rescues t...

    Woosuk Chung, Su Yeon Choi, Eunee Lee, Haram Park, Jaeseung Kang… in Nature Neuroscience (2015)