104 Result(s)
within
Eun-** Yoon
Science, Humanities and Social Sciences, multidisciplinary
-
Article
Open AccessChip collection of hepatocellular carcinoma based on O2 heterogeneity from patient tissue
Hepatocellular carcinoma frequently recurs after surgery, necessitating personalized clinical approaches based on tumor avatar models. However, location-dependent oxygen concentrations resulting from the dual ...
-
Article
Open AccessDevelopment and validation of an interpretable model for predicting sepsis mortality across care settings
There are numerous prognostic predictive models for evaluating mortality risk, but current scoring models might not fully cater to sepsis patients’ needs. This study developed and validated a new model for sep...
-
Article
Open AccessQuantitative analysis of blooming artifact caused by calcification based on X-ray energy difference using computed tomography
Blooming artifacts caused by calcifications appearing on computed tomography (CT) images lead to an underestimation of the coronary artery lumen size, and higher X-ray energy levels are suggested to reduce the...
-
Article
Open AccessHistopathologic image–based deep learning classifier for predicting platinum-based treatment responses in high-grade serous ovarian cancer
Platinum-based chemotherapy is the cornerstone treatment for female high-grade serous ovarian carcinoma (HGSOC), but choosing an appropriate treatment for patients hinges on their responsiveness to it. Current...
-
Article
Open AccessChemokine expression in sera of patients with microscopic polyangiitis and granulomatosis with polyangiitis
We evaluated chemokine expression and its correlation with disease activity in patients with microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA) (MPA/GPA). Serum CCL2, CCL4, CCL19, CXCL1,...
-
Article
Open AccessLongitudinal long term follow up investigation on the carcinogenic impact of polyhexamethylene guanidine phosphate in rat models
Polyhexamethylene guanidine phosphate (PHMG-p) is a major component in humidifier disinfectants, which cause life-threatening lung injuries. However, to our knowledge, no published studies have investigated as...
-
Article
Open AccessUnraveling the role of the mitochondrial one-carbon pathway in undifferentiated thyroid cancer by multi-omics analyses
The role of the serine/glycine metabolic pathway (SGP) has recently been demonstrated in tumors; however, the pathological relevance of the SGP in thyroid cancer remains unexplored. Here, we perform metabolomi...
-
Article
Open AccessDensity clustering-based automatic anatomical section recognition in colonoscopy video using deep learning
Recognizing anatomical sections during colonoscopy is crucial for diagnosing colonic diseases and generating accurate reports. While recent studies have endeavored to identify anatomical regions of the colon u...
-
Article
Open AccessDevelopment of a novel prediction model for differential diagnosis between spinal myxopapillary ependymoma and schwannoma
Spinal myxopapillary ependymoma (MPE) and schwannoma represent clinically distinct intradural extramedullary tumors, albeit with shared and overlap** magnetic resonance imaging (MRI) characteristics. We aime...
-
Article
Open AccessProteomic analysis reveals activation of platelet- and fibrosis-related pathways in hearts of ApoE−/− mice exposed to diesel exhaust particles
Air pollution is an environmental risk factor linked to multiple human diseases including cardiovascular diseases (CVDs). While particulate matter (PM) emitted by diesel exhaust damages multiple organ systems,...
-
Article
Open AccessAllelic hierarchy for USH2A influences auditory and visual phenotypes in South Korean patients
When medical genetic syndromes are influenced by allelic hierarchies, mutant alleles have distinct effects on clinical phenotypes. Genotype–phenotype correlations for Usher syndrome type 2 (USH2) suggest that ...
-
Article
Open AccessHarmful effect of repetitive intravenous iodinated contrast media administration on the long-term renal function of patients with early gastric cancer
This retrospective study investigated whether repetitive exposure to intravenous iodinated contrast media (ICM) affects long-term renal function in patients who undergo curative surgery for early gastric cance...
-
Article
Open AccessThe lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism
Arachidonic and adrenic acids in the membrane play key roles in ferroptosis. Here, we reveal that lipoprotein-associated phospholipase A2 (Lp-PLA2) controls intracellular phospholipid metabolism and contribute...
-
Article
Open AccessEtiology and clinical characteristics of acute viral hepatitis in South Korea during 2020–2021: a prospective multicenter study
This prospective, 12-center study investigated the etiology and clinical characteristics of acute viral hepatitis (AVH) during 2020–2021 in South Korea, and the performance of different diagnostic methods for ...
-
Article
Open AccessPrevalence of cancer-related fatigue based on severity: a systematic review and meta-analysis
Cancer-related fatigue (CRF) affects therapeutic compliance and clinical outcomes including recurrence and mortality. This study aimed to comprehensively and comparatively assess the severity-based prevalence ...
-
Article
Open AccessCurrent treatments for endometriosis in South Korea: an analysis of nationwide data from 2010 to 2019
While a wide range of treatments, including medical therapies and surgery, are used to manage endometriosis, the characteristics and treatment status of patients who received these treatments have not been inv...
-
Article
Open AccessGenome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population
Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small fraction of lung adenocarcinoma heritability. Here, we conducted a two-stage genome-wide association study o...
-
Article
Open AccessPCR-like performance of rapid test with permselective tunable nanotrap
Highly sensitive rapid testing for COVID-19 is essential for minimizing virus transmission, especially before the onset of symptoms and in asymptomatic cases. Here, we report bioengineered enrichment tools for...
-
Article
Open AccessSsu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation
Brown adipose tissue (BAT) plays a pivotal role in maintaining body temperature and energy homeostasis. BAT dysfunction is associated with impaired metabolic health. Here, we show that Ssu72 phosphatase is ess...
-
Article
Open AccessAutomatic diagnosis of retention pseudocyst in the maxillary sinus on panoramic radiographs using a convolutional neural network algorithm
The evaluation of the maxillary sinus is very important in dental practice such as tooth extraction and implantation because of its proximity to the teeth, but it is not easy to evaluate because of the overlap...
