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Article
Thoracic manifestation of Wegener's granulomatosis: CT findings in 30 patients
Our objective was to describe the CT findings of thoracic Wegener's granulomatosis. At presentation, both conventional and thin-section CT scans were available in 30 patients with Wegener's granulomatosis. Se...
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Article
A phase II study of dose-intensified weekly concomitant administration of cisplatin and irinotecan in chemonaive patients with extensive-disease small-cell lung cancer
Irinotecan/cisplatin (IP) is an active regimen for extensive-disease small-cell lung cancer (ED-SCLC). However, the optimal dose/schedule is unsettled. To evaluate the efficacy and safety of a dose-intensified...
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Chapter and Conference Paper
Small Field Scanning Mammography Using Polycapillary Optics Collimating Beam
Mammography is a unique diagnostic tool to detect breast cancer by identification of tumor masses and microcalcifications. High spatial resolution and image contrast is essential at mammography system with low...
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Article
A randomized phase-III trial of docetaxel/capecitabine versus doxorubicin/cyclophosphamide as primary chemotherapy for patients with stage II/III breast cancer
We aimed to determine the efficacies of a non-anthracycline-containing regimen, docetaxel/capecitabine (TX), in comparison with an anthracycline-containing regimen, doxorubicin/cyclophosphamide (AC), as primar...
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Article
Major response to sunitinib (Sutene®) in metastatic malignant phyllodes tumor of breast
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Article
Primary systemic therapy with intermittent weekly paclitaxel plus gemcitabine in patients with stage II and III breast cancer: a phase II trial
The purpose of this study was to evaluate pathologic complete response (pCR) rates and adverse events with primary systemic therapy (PST) of intermittent weekly paclitaxel and gemcitabine in patients with stag...
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Article
Risk Factors for Malignancy in Benign Papillomas of the Breast on Core Needle Biopsy
This study was designed to evaluate the clinical and pathologic parameters of benign papillomas diagnosed on core needle biopsy (CNB) and predict malignancy risk after surgical excision.
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Article
Worse prognosis of metaplastic breast cancer patients than other patients with triple-negative breast cancer
The present study was designed to assess the clinical characteristics and outcomes of metaplastic breast cancer (MBC) compared to general invasive ductal carcinoma (IDC) and the triple-negative subtype (TN-IDC...
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Article
Suppression of Glutamate-Induced Excitotoxicity by 2-Cyclopropylimino-3-methyl-1,3-thiazoline Hydrochloride in Rat Glial Cultures
We have screened new drugs with a view to develo** effective drugs against glutamate-induced excitotoxicity. In the present work, we show effects of a new drug, 2-cyclopropylimino-3-methyl-1,3-thiazoline hyd...
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Article
Suppression of lipopolysaccharide-induced microglial activation by a benzothiazole derivative
We previously reported that KHG21834, a benzothiazole derivative, attenuates the beta-amyloid (Aβ)-induced degeneration of both cortical and mesencephalic neurons in vitro. Central nervous system inflammation med...
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Article
Research on factors influencing intention to use DMB using extended IS success model
The commercialization of DMB (Digital Multimedia Broadcasting), a portable multimedia broadcasting technology, has begun. Although DMB has been introduced internationally, the distribution has been limited to ...
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Article
Open AccessThe invasive lobular carcinoma as a prototype luminal A breast cancer: A retrospective cohort study
Although the invasive lobular carcinoma (ILC) is the second most frequent histologic subtype in Western countries, its incidence is much lower in Asia, and its characteristics are less well known.
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Article
Neuroprotective Effects of 2-Cyclopropylimino-3-Methyl-1,3-Thiazoline Hydrochloride Against Oxidative Stress
Oxidative stress, glutamate excitotoxicity, and inflammation are the important pathological mechanisms in neurodegenerative diseases. Recently, we reported that 2-cyclopropylimino-3-methyl-1,3-thiazoline hydro...
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Article
Predictive factors of pathologic complete response and clinical tumor progression after preoperative chemotherapy in patients with stage II and III breast cancer
Background This study aimed to define predictive factors of pathologic complete response (pCR) and disease progression in stage II and III breast cancer patients. Patients and Methods Thr...
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Article
Purification of antioxidative peptide from peptic hydrolysates of Mideodeok (Styela clava) flesh tissue
In this study, an antioxidative peptide was obtained by hydrolyzation of mideodeok (Styela clava) flesh tissue with various proteases and purified through gel filtration chromatography and reverse phage-HPLC (RPH...
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Article
Anti-inflammatory activity of phlorotannin-rich fermented Ecklonia cava processing by-product extract in lipopolysaccharide-stimulated RAW 264.7 macrophages
In this study, fermentation was employed as a tool to further increase the bioactive potential of processing by-product from a brown seaweed, Ecklonia cava, which can be obtained from food and cosmetic industries...
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Article
Open AccessHistorical review of the List of Occupational Diseases recommended by the International Labour organization (ILO)
The list of occupational diseases established in the international and national legal system has played important roles in both prevention of and compensation for workers’ diseases. This report reviewed the hi...
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Article
Open AccessTwo Cases of Lung Cancer in Foundry Workers
Iron and steel foundry workers are exposed to various toxic and carcinogenic substances including crystalline silica, polycyclic aromatic hydrocarbons, and arsenic. Studies have been conducted on lung cancer i...
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Article
Open AccessAssessment of Arsenic Exposure by Measurement of Urinary Speciated Inorganic Arsenic Metabolites in Workers in a Semiconductor Manufacturing Plant
The purpose of this study was to evaluate the exposure to arsenic in preventive maintenance (PM) engineers in a semiconductor industry by detecting speciated inorganic arsenic metabolites in the urine.
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Article
Open AccessA Case of Tracheal Adenoid Cystic Carcinoma in a Worker Exposed to Rubber Fumes
Primary tracheal tumors occur infrequently, accounting for less than 0.1% of all tumors. Adenoid cystic carcinoma (ACC) is the second most common type of malignancy of the trachea after squamous cell carcinoma...
