-
Article
Open AccessMicrobial metabolomics in open microscale platforms
The microbial secondary metabolome encompasses great synthetic diversity, empowering microbes to tune their chemical responses to changing microenvironments. Traditional metabolomics methods are ill-equipped t...
-
Article
Open AccessMicrobial volatile communication in human organotypic lung models
We inhale respiratory pathogens continuously, and the subsequent signaling events between host and microbe are complex, ultimately resulting in clearance of the microbe, stable colonization of the host, or act...
-
Article
Open AccessUser-defined morphogen patterning for directing human cell fate stratification
Concentration gradients of biochemical stimuli such as morphogens play a critical role in directing cell fate patterning across species and throughout development but are not commonly recapitulated in vitro. Whil...
-
Article
Open AccessFungal oxylipins direct programmed developmental switches in filamentous fungi
Filamentous fungi differentiate along complex developmental programs directed by abiotic and biotic signals. Currently, intrinsic signals that govern fungal development remain largely unknown. Here we show tha...
-
Article
Miniaturizing chemistry and biology using droplets in open systems
Open droplet microfluidic systems manipulate droplets on the picolitre-to-microlitre scale in an open environment. They combine the compartmentalization and control offered by traditional droplet-based microfl...
-
Article
Open AccessPoint-of-care BCR::ABL1 transcript monitoring using capillary dried blood in chronic myeloid leukemia patients
