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  1. Article

    Open Access

    Microbial metabolomics in open microscale platforms

    The microbial secondary metabolome encompasses great synthetic diversity, empowering microbes to tune their chemical responses to changing microenvironments. Traditional metabolomics methods are ill-equipped t...

    Layla J. Barkal, Ashleigh B. Theberge, Chun-Jun Guo, Joe Spraker in Nature Communications (2016)

  2. Article

    Open Access

    Microbial volatile communication in human organotypic lung models

    We inhale respiratory pathogens continuously, and the subsequent signaling events between host and microbe are complex, ultimately resulting in clearance of the microbe, stable colonization of the host, or act...

    Layla J. Barkal, Clare L. Procknow, Yasmín R. Álvarez-García in Nature Communications (2017)

  3. Article

    Open Access

    User-defined morphogen patterning for directing human cell fate stratification

    Concentration gradients of biochemical stimuli such as morphogens play a critical role in directing cell fate patterning across species and throughout development but are not commonly recapitulated in vitro. Whil...

    Mary C. Regier, Jacob J. Tokar, Jay W. Warrick, Lil Pabon in Scientific Reports (2019)

  4. Article

    Open Access

    Fungal oxylipins direct programmed developmental switches in filamentous fungi

    Filamentous fungi differentiate along complex developmental programs directed by abiotic and biotic signals. Currently, intrinsic signals that govern fungal development remain largely unknown. Here we show tha...

    Mengyao Niu, Breanne N. Steffan, Gregory J. Fischer in Nature Communications (2020)