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Open AccessEpigenetic silencing of UBXN8 contributes to leukemogenesis in t(8;21) acute myeloid leukemia
The formation of the RUNX1-RUNX1T1 fusion protein, resulting from the t(8;21) translocation, is considered to be one of the initiating events of t(8;21) acute myeloid leukemia (AML). However, the mechanisms of...