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  1. No Access

    Article

    A polymorphism in PTPN2 gene is associated with an earlier onset of type 1 diabetes

    The Wellcome Trust Case Control Consortium (WTCCC) genome-wide study found association of PTPN2 with three autoimmune diseases, among them is type 1 diabetes (T1D). This result was confirmed by a follow-up study ...

    Laura Espino-Paisan, Hermenegildo de la Calle, Miguel Fernández-Arquero… in Immunogenetics (2011)

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    Article

    IL4 in the 5q31 context: association studies of type 1 diabetes and rheumatoid arthritis in the Spanish population

    IL4, the gene coding the prototypic Th2 cytokine, has been frequently studied in the context of several inflammatory conditions, but conclusive results have not been obtained. This gene i...

    Concepción Nuñez, Jose Luis Santiago, Jezabel Varadé… in Immunogenetics (2008)

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    Article

    Influence of the inducible nitric oxide synthase gene (NOS2A) on inflammatory bowel disease susceptibility

    The great amount of nitric oxide (NO) produced by the inducible isoform of NO synthase (iNOS) exerts deleterious effects, and iNOS expression is raised in the colonic mucosa of inflammatory bowel disease (IBD)...

    M. Carmen Martín, Alfonso Martinez, J. Luis Mendoza, Carlos Taxonera… in Immunogenetics (2007)