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  1. No Access

    Chapter

    Anesthetics Drug Pharmacodynamics

    Anesthesia cannot be defined in an unambiguous manner. The essential components of general anesthesia are absence of consciousness and pain. This translates into two particular qualities: (1) sedation and hypn...

    P. Bischoff, G. Schneider, E. Kochs in Modern Anesthetics (2008)

  2. No Access

    Chapter and Conference Paper

    Pain relief by ketamine

    Although advances in techniques for anaesthesia, surgery, and the protection of organs have resulted in reductions in age- and risk-adjusted mortality and morbidity, the incidence of perioperative pain has cha...

    S. Himmelseher, E. Kochs in Anaesthesia, Pain, Intensive Care and Emer… (2004)

  3. No Access

    Chapter and Conference Paper

    Neuroprotection by ketamine

    The fundamental clinical obstacle to the use of ketamine for neuroprotection is the historical textbook dogma that ketamine is contraindicated in patients at risk of increases in intracranial pressure (ICP) [1...

    S. Himmelseher, E. Kochs in Anaesthesia, Pain, Intensive Care and Emer… (2004)

  4. No Access

    Article

    Haemodynamic changes and skeletal muscle oxygen tension during complete blood exchange with ultrapurified polymerized bovine haemoglobin

    Objective: The study investigates the effect of continuous blood exchange with ultrapurified, polymerized bovine haemoglobin (UPBH) in comparison to hetastarch on haemodynamics, oxygen t...

    T. G. Standl, W. Reeker, G. Redmann, E. Kochs, C. Werner… in Intensive Care Medicine (1997)

  5. No Access

    Chapter

    Studies on Tumor Oxygenation in a Rat Rhabdomyo-Sarcoma during Fractionated Irradiation

    The oxygenation status of a tumor is certainly one of the major factors which influences the response of a tumor to radiotherapy (7, 9, 16, 22). Due to a chaotic and temporarily fluctuating tumor blood perfusi...

    F. Zywietz, W. Reeker, E. Kochs in Oxygen Transport to Tissue XVII (1996)

  6. No Access

    Chapter and Conference Paper

    Somatosensory Evoked Potentials: Objective Measures of Antinociception in the Anesthetized Patient?

    The most critical problems in pain research and clinical practice are the quantitation of nociception and the subjective experience of pain. From a physiologic point of view, pain is a consequence of the activ...

    E. Kochs in Control and Automation in Anaesthesia (1995)

  7. No Access

    Chapter

    “Paradoxical Arousal” During Isoflurane/Nitrous Oxide Anesthesia: Quantitative Topographical EEG Analysis

    Electroencephalogram (EEG) recordings have been used for the evaluation of drug effects on brain electrical activity, and numerous studies suggest that EEG measures may be useful for the assessment of depth of...

    P. Bischoff, E. Kochs, J. Schulte am Esch in Central Nervous System Monitoring in Anest… (1994)

  8. No Access

    Chapter

    Anesthesia and Somatosensory Evoked Responses

    Intraoperative monitoring of somatosensory evoked potentials (SEP) is used increasingly to improve monitoring of neural tracts at risk during scoliosis surgery, surgical procedures involving the thoracic aorta...

    E. Kochs, P. Bischoff in Central Nervous System Monitoring in Anesthesia and Intensive Care (1994)

  9. No Access

    Chapter and Conference Paper

    Influences of Various Respiratory and Circulatory Conditions on Muscle Tissue Oxygenation in Critically Ill Patients

    Inadequate tissue perfusion results in inadequate oxygen transport to the mitochondria. The function of the circulatory systems is to guarantee an adequate cellular oxygen delivery to replace the oxygen used a...

    J. am Schulte Esch, H. W. Bause, E. Kochs in Yearbook of Intensive Care and Emergency M… (1992)