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  1. Article

    Open Access

    EuroClonality/BIOMED-2 guidelines for interpretation and reporting of Ig/TCR clonality testing in suspected lymphoproliferations

    PCR-based immunoglobulin (Ig)/T-cell receptor (TCR) clonality testing in suspected lymphoproliferations has largely been standardized and has consequently become technically feasible in a routine diagnostic se...

    A W Langerak, P J T A Groenen, M Brüggemann, K Beldjord, C Bellan, L Bonello… in Leukemia (2012)

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  2. Article

    Clonality analysis in lymphoproliferative disease using the BIOMED-2 multiplex PCR protocols: experience from the EuroClonality group EQA scheme

    The BIOMED-2 primers and PCR protocols for the detection of clonal proliferations in lymphoproliferative disease are well established and are used in many Molecular Pathology laboratories worldwide due to thei...

    Susan Harris, M. Bruggemann, P. J. T. A. Groenen… in Journal of Hematopathology (2012)

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  3. No Access

    Article

    Recurrent finding of the FIP1L1-PDGFRA fusion gene in eosinophilia-associated acute myeloid leukemia and lymphoblastic T-cell lymphoma

    The FIP1L1-PDGFRA fusion gene has been described in patients with eosinophilia-associated myeloproliferative disorders (Eos-MPD). Here, we report on seven FIP1L1-PDGFRA-positive patients who presented with acute ...

    G Metzgeroth, C Walz, J Score, R Siebert, S Schnittger, C Haferlach, H Popp… in Leukemia (2007)

  4. No Access

    Article

    Improved reliability of lymphoma diagnostics via PCR-based clonality testing: — Report of the BIOMED-2 Concerted Action BHM4-CT98-3936

    The diagnosis of malignant lymphoma is a recognized difficult area in histopathology. Therefore, detection of clonality in a suspected lymphoproliferation is a valuable diagnostic criterion. We have developed ...

    J H J M van Krieken, A W Langerak, E A Macintyre, M Kneba, E Hodges… in Leukemia (2007)