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  1. Article

    Open Access

    Epigenetic profiling demarcates molecular subtypes of muscle-invasive bladder cancer

    Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease that often recurs despite aggressive treatment with neoadjuvant chemotherapy and (radical) cystectomy. Basal and luminal molecular subtypes have...

    K. E. van der Vos, D. J. Vis, E. Nevedomskaya, Y. Kim, W. Choi… in Scientific Reports (2020)

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  2. No Access

    Article

    Endogenous androgen receptor proteomic profiling reveals genomic subcomplex involved in prostate tumorigenesis

    Androgen receptor (AR) is a key player in prostate cancer development and progression. Here we applied immunoprecipitation mass spectrometry of endogenous AR in LNCaP cells to identify components of the AR tra...

    S Stelloo, E Nevedomskaya, Y Kim, L Hoekman, O B Bleijerveld, T Mirza… in Oncogene (2018)

  3. No Access

    Article

    Systematic integration of molecular profiles identifies miR-22 as a regulator of lipid and folate metabolism in breast cancer cells

    Dysregulated microRNA (miRNA) mediate malignant phenotypes, including metabolic reprogramming. By performing an integrative analysis of miRNA and metabolome data for the NCI-60 cell line panel, we identified a...

    C Koufaris, G N Valbuena, Y Pomyen, G D Tredwell, E Nevedomskaya, C-HE Lau… in Oncogene (2016)