35 Result(s)
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Article
Clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma
The clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma (ND-DLBCL) remains largely unexplored. One hundred ND-DLBCL patients were consecutively enrolled as training c...
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Open AccessMulti-dimensional cell-free DNA-based liquid biopsy for sensitive early detection of gastric cancer
Gastric cancer is the fifth most common cancer type. Most patients are diagnosed at advanced stages with poor prognosis. A non-invasive assay for the detection of early-stage gastric cancer is highly desirable...
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Article
Novel ratio-expressions of genes enables estimation of wound age in contused skeletal muscle
Given that combination with multiple biomarkers may well raise the predictive value of wound age, it appears critically essential to identify new features under the limited cost. For this purpose, the present ...
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Open AccessAssessment of Autologous Blood marker localIzation and intraoperative coLonoscopy localIzation in laparoscopic colorecTal cancer surgery (ABILITY): a randomized controlled trial
Laparoscopic colorectal surgery has been proved to have similar oncological outcomes with open surgery. Due to the lack of tactile perception, surgeons may have misjudgments in laparoscopic colorectal surgery....
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MTDH-stabilized DDX17 promotes tumor initiation and progression through interacting with YB1 to induce EGFR transcription in Hepatocellular Carcinoma
Metadherin (MTDH) is a well-established oncogene in various cancers including Hepatocellular Carcinoma (HCC). However, the precise mechanism through which MTDH promotes cancer-related signaling pathways in HCC...
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Article
Open AccessQuality and accuracy of gastric cancer related videos in social media videos platforms
Gastric cancer is a major public health problem worldwide. Social media has affected public’s daily lives in ways no one ever thought possible. Both TikoTok and its Chinese version Douyin are the most popular ...
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Role of Neuroimmune Interactions in COVID-19-related Cardiovascular Damage
Coronavirus disease 2019 (COVID-19) has caused a global pandemic impacting over 200 countries/regions and more than 200 million patients worldwide. Among the infected patients, there is a high prevalence of CO...
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Open AccessSafety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial
Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Blocking CD147 via anti-CD147 antibody could suppress the in vitro SAR...
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Article
Risk factors for subclinical renal damage and its progression: Hanzhong Adolescent Hypertension Study
Chronic kidney disease (CKD) is a global public health problem, including in China. The aim of this study was to identify the risk factors for the development and progression of subclinical renal disease (SRD)...
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Article
Relationship Between Ablation Lesion Size Estimated by Ablation Index and Different Ablation Settings—an Ex Vivo Porcine Heart Study
This study aimed to verify the reliability of ablation index (AI) for ablation lesion estimating with different settings for radiofrequency (RF) parameters: power, impedance, contact angles, irrigation rate, t...
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Open AccessCorrection to: Cardiac rupture complicating acute myocardial infarction: the clinical features from an observational study and animal experiment
An amendment to this paper has been published and can be accessed via the original article.
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Article
Open AccessCardiac rupture complicating acute myocardial infarction: the clinical features from an observational study and animal experiment
Cardiac rupture (CR) is a fatal complication of ST-elevation myocardial infarction (STEMI) with its incidence markedly declined in the recent decades. However, clinical features of CR patients now and the effe...
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Article
CO2 Laser Moxibustion for Knee Osteoarthritis: Study Protocol for A Multicenter, Double-blind, Randomized Controlled Trial
Knee osteoarthritis (OA) is a major cause of disability among the older adults. Few treatments are safe and effective. Moxibustion is commonly used in treating knee OA in Chinese medicine (CM). CO2 Laser moxibust...
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Article
Intratumor δ-catenin heterogeneity driven by genomic rearrangement dictates growth factor dependent prostate cancer progression
Only a small number of genes are bona fide oncogenes and tumor suppressors such as Ras, Myc, β-catenin, p53, and APC. However, targeting these cancer drivers frequently fail to demonstrate sustained cancer remiss...
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Effect of China’s Universal Two-child Policy on the Rate of Cesarean Delivery: A Case Study of a Big Childbirth Center in China
China’s universal two-child policy was released in October of 2015. How would this new policy influence the rate of overall cesarean delivery (CD) in China? The objective of this paper is to investigate the tr...
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Article
Leonurine: From Gynecologic Medicine to Pleiotropic Agent
Leonurus japonicus Houtt, a Chinese traditional herbal medicine, has been widely used to cure gynecological diseases, such as incomplete abortion and menoxenia. Leonurine, a major active alkaloid compound only be...
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Article
Open AccessExtracellular vesicles from human urine-derived stem cells prevent osteoporosis by transferring CTHRC1 and OPG
Osteoporosis is a debilitating bone disease affecting millions of people. Here, we used human urine-derived stem cells (USCs), which were noninvasively harvested from unlimited and easily available urine, as a...
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Article
Effect of Shuwei Decoction (舒胃汤) on rats with functional dyspepsia
To investigate the effects of Shuwei Decoction (舒胃汤, SWD) on gastric emptying, serum stem cell factor (SCF), the content of serum nitric oxide (NO), and structure change of interstitial cells of Cajal (ICC) in...
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Article
Open AccessProceedings of the 7th Biannual International Symposium on Nasopharyngeal Carcinoma 2015
A1 Hope and despair in the current treatment of nasopharyngeal cancer
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Article
Sheehan’s syndrome in **njiang: Clinical characteristics and laboratory evaluation of 97 patients
OBJECTIVE: To evaluate the clinical and hormonal characteristics of patients with Sheehan’s syndrome in **njiang, China. METHODS: 97 cases diagnosed as Sheehan’s syndrome in our hospital from 1999 to 2013 were...
