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  1. Article

    Open Access

    Purity and Uncertainty Study of CRM Betulin by DSC

    Betulin (BE) can be obtained from many plants, such as those belonging Betulaceae family, and pharmacological investigations showed its notable biological properties and good potential for food and pharmaceuti...

    Li Zhang, Peng-Hui Yuan, De-Zhi Yang, Yan-Cai Bi in Natural Products and Bioprospecting (2020)

  2. Article

    Open Access

    Analysis of Four Solvatomorphs of Betulin by TG–DTA–EI/PI–MS System Equipped with the Skimmer-Type Interface

    Betulin (BE) has exceedingly become a potential natural product, providing multiple pharmacological and biological activities, including anti-cancer, anti-viral, and anti-inflammatory benefits. Previous research ...

    Peng-Hui Yuan, Yan-Cai Bi, Bin Su, De-Zhi Yang in Natural Products and Bioprospecting (2020)

  3. No Access

    Chapter

    Berberine

    Berberine is a quaternary ammonium salt that is found in some plants such as huanglian (Rhizoma coptidis), huangbo (Phellodendri Chinensis Cortex), and sankezhen (Berberidis Radix). Berberine hydrochloride has ex...

    Lian-Hua Fang, **-Hua Wang, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

  4. No Access

    Chapter

    Atropine

    Atropine is a poisonous white crystalline alkaloid extracted from roots and leaves of dianqiecao (Belladonnae Herba) and mantuoluo (Mandala). Atropine sulphate is commonly used in clinics. Atropine is a blocker o...

    Lian-Hua Fang, **-Hua Wang, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

  5. No Access

    Chapter

    Matrine

    Matrine is an alkaloid extracted by organic solvents from the dry roots, plants, and fruits of kushen (Sophora flavescens Ait). Matrine has significant effects of negative frequency and positive inotropic action,...

    Li Gao, Li-Da Du, Xue-Mei Qin, **-Hua Wang in Natural Small Molecule Drugs from Plants (2018)

  6. No Access

    Chapter

    Strychnine

    Strychnine, first discovered in 1818, was the first alkaloid to be identified in plants of maqianzi (Strychnos nux-vomica Linn.). Pharmacological effect of strychnine is mainly manifested in the central nervous s...

    Li Gao, Li-Da Du, Xue-Mei Qin, **-Hua Wang in Natural Small Molecule Drugs from Plants (2018)

  7. No Access

    Chapter

    Erycibe Alkaloid II

    Erycibe alkaloid II belongs to scopolamine alkaloids, whose chemical structure is different from other known cholinomimetic drugs. Erycibe alkaloid II has the remarkable therapeutic effect on glaucoma by contr...

    Zhi-Hong Yang, Li-Da Du, Shou-Bao Wang in Natural Small Molecule Drugs from Plants (2018)

  8. No Access

    Chapter

    Vinblastine and Vincristine

    Vinblastine and vincristine are all extracted from Catharanthus roseus, which is a common Apocynaceae ornamental plant. Vinblastine and vincristine drugs have a strong inhibitory effect on monozygotic leukemia, b...

    You-Wen Zhang, **ang-Ying Kong, **-Hua Wang in Natural Small Molecule Drugs from Plants (2018)

  9. No Access

    Chapter

    Cytisine

    Cytisine is an alkaloid, which is isolated from Laburnum and Cytisus of the family Fabaceae. Cytisine has a similar chemical structure to that of nicotine, and it possesses selective binding affinity for neuronal...

    **ao-Ming Zhu, Li-Da Du, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

  10. No Access

    Chapter

    Eserine

    Eserine is an alkaloid extracted from Physostigma venenosum, which is a reversible acetylcholinesterase (AChE) inhibitor. Eserine is the same as acetylcholine, which can combine with cholinesterase, while AChE in...

    Yi-Huang Lin, Lian-Hua Fang, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

  11. No Access

    Chapter

    Pilocarpine

    Pilocarpine is an alkaloid extracted from Pilocarpus jaborandi, which is one of cholinomimetic drugs. Pilocarpine activates cholinergic M-receptor and has an obvious effect on eyes and salivary glands. Pilocarpin...

    Yi-Huang Lin, Lian-Hua Fang, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

  12. No Access

    Chapter

    Cocaine

    Cocaine, is also called cocain, was mainly separated from the leaves of coca. Cocaine is white crystal powder and odorless. It is insoluble in water, soluble in chloroform, ethyl ether, ethanol, and other orga...

    Ying Zhao, **-Hua Wang, **u-Ying Yang in Natural Small Molecule Drugs from Plants (2018)

  13. No Access

    Chapter

    Ephedrine

    Ephedrine, also called ephedrine ingot, L-ephedrine, is from dry grass stems of ephedra plants such as ephedra, Zhong ephedra, and Equisetum ephedra. Ephedrine is a white needle-like crystal or crystalline pow...

    **-Hua Wang, **u-Ying Yang, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

  14. No Access

    Chapter

    Galantamine

    Galantamine is an Amaryllidaceae alkaloid which is first obtained from the plant of snowdrop (Galanthus nivalis). Although the plants of Galanthus are native species in many areas in Europe, its earliest pharmace...

    Tian-Tian Lei, **-Hua Wang, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

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    Chapter

    Camptothecin

    As an alkaloid derived from Camptotheca acuminata, camptothecin exerted its anticancer activity by specifically targeted topoisomerase I. The intolerable toxicity and poor solubility and stability in vivo of camp...

    De Kang, Ai-Lin Liu, **-Hua Wang, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

  16. No Access

    Chapter

    Daidzein

    Daidzein mainly comes from leguminous plants, the seeds of soybean, red clover grass, or all Pueraria roots. Daidzein is a kind of isoflavone compound. It is mainly used for the treatment of hypertension, coronar...

    Zi-Ran Niu, Lian-Hua Fang, Gui-Fen Qiang in Natural Small Molecule Drugs from Plants (2018)

  17. No Access

    Chapter

    Securinine

    Securinine is derived from the leaf of securinega suffruticosa Rehd., in which securinine is the most important alkaloid. Securinine mainly has nerve pharmacological activity; it also has antitumor, anti-infla...

    Dan-Shu Wang, Lian-Hua Fang, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

  18. Chapter

    Andrographolide

    Andrographolide is a diterpene lactone compound extracted from Andrographis paniculata (Burm. F) Nees, which is commonly used as traditional Chinese medicine. Andrographolide has effects of anti-inflammatory, ant...

    Yu Yan, Lian-Hua Fang, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

  19. No Access

    Chapter

    Rutin

    Rutin is widely found in nature and is almost contained in all of the Rutaceae and Sectaceae plants. As a flavonoid substance, rutin has a significant protective effect on the cardiovascular system. Rutin and ...

    Bi-Yu Hou, Li Zhang, **-Hua Wang, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

  20. No Access

    Chapter

    Tanshinone IIA

    Tanshinone IIA is extracted from the roots of Salvia miltiorrhiza Bge., which exhibits a variety of pharmacological effects, such as promoting blood circulation and opening the energy channels. In the long histor...

    Yu-Cai Chen, Lian-Hua Fang, Guan-Hua Du in Natural Small Molecule Drugs from Plants (2018)

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