392 Result(s)
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Biotechnology
Nanotechnology
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Article
Open AccessNanobody peptide conjugate: a novel CD163 based broad neutralizing strategy against porcine reproductive and respiratory syndrome virus
Porcine reproductive and respiratory syndrome virus (PRRSV) is a prevalent swine pathogen, which has caused adverse impact on the global swine industry for almost 30 years. However, due to the immune suppressi...
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Defect-modulated and heteroatom-functionalized Ti3-xC2Ty MXene 3D nanocavities induce growth of MoSe2 nanoflakes toward electrocatalytic hydrogen evolution in all pH electrolytes
Reducing kinetic energy barriers and develo** accessible active sites are critical to deliver high hydrogen evolution reaction (HER) efficiency. In this paper, we synthesized defect-modulated and heteroatom ...
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Open AccessLPA1 antagonist-derived LNPs deliver A20 mRNA and promote anti-fibrotic activities
Activated fibroblasts are major mediators of pulmonary fibrosis. Fibroblasts are generally found in the connective tissue but upon activation can generate excess extracellular matrix (ECM) in the lung intersti...
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Open AccessDe novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation
The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...
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Erratum to: Self-enhancing photothermal conversion of 2D Weyl semimetal WTe2 with topological surface states for efficient solar vapor generation
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Edge dislocation-induced strains break the limit of PtNi alloys in boosting Pt mass activity for efficient alkaline hydrogen evolution
Creating lattice defects and alloying to produce strain effect in Pt-based bimetallic alloys are both effective methods to optimize the crystal and electronic structure and improve the electrocatalytic perform...
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Rationally construction of atomic-precise interfacial charge transfer channel and strong build-in electric field in nanocluster-based Z-scheme heterojunctions with enhanced photocatalytic hydrogen production
The lack of effective charge transfer driving force and channel limits the electron directional migration in nanoclusters (NC)-based heterostructures, resulting in poor photocatalytic performance. Herein, a Z-...
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Non-bonding modulations between single atomic cerium and monodispersed selenium sites towards efficient oxygen reduction
Currently, dual atomic catalysts (DACs) with neighboring active sites for oxygen reduction reaction (ORR) still meet lots of challenges in the synthesis, especially the construction of atomic pairs of elements...
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A high-performance electrocatalyst for oxygen reduction derived from copolymer-anchored polyoxometalates
The development and synthesis of cathode electrocatalysts with high activity and durable stability for metal-air batteries is an important challenge in the area of electrocatalysis. Herein, we introduce a novel i...
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Ultrasmall copper-based clusterzymes ameliorate Achilles tendinopathy by inhibiting acute oxidative stress
Tendinopathy is a prevalent musculoskeletal disorder, accounting for over 30% of musculoskeletal lesions. However, current therapeutic strategies for tendinopathy are limited and often yield unsatisfactory cli...
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Engineered interface of three-dimensional coralliform NiS/FeS2 heterostructures for robust electrocatalytic water cleavage
Heterojunction structures improve the intrinsic activity of electrocatalysts by enhancing the charge transfer between the catalyst and the electrode. In this paper, the NiS/FeS2 heterostructured electrocatalyst i...
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Cathodic corrosion as a facile and universal method for scalable preparation of powdery single atom electrocatalysts
Top-down strategy has been widely applied for synthesis of metal single atom catalysts (SACs) via converting metal nanoparticles or bulk metals into atomically dispersed species. Here, we report a simple elect...
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Open AccessTherapeutic nanobodies against SARS-CoV-2 and other pathogenic human coronaviruses
Nanobodies, single-domain antibodies derived from variable domain of camelid or shark heavy-chain antibodies, have unique properties with small size, strong binding affinity, easy construction in versatile for...
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Open AccessGlutathione-depleting Liposome Adjuvant for Augmenting the Efficacy of a Glutathione Covalent Inhibitor Oridonin for Acute Myeloid Leukemia Therapy
Discrepancies in the utilization of reactive oxygen species (ROS) between cancer cells and their normal counterparts constitute a pivotal juncture for the precise treatment of cancer, delineating a noteworthy ...
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Trace Pd alloyed with Au to boost Au/uncalcined TS-1 catalyzed propane hydro-oxidation to acetone
Selective oxidation of propane to acetone (AC) with H2 and O2 provides a direct route to convert low-cost propane into value-added products. Unfortunately, the catalytic activity of conventional Au/Ti-based catal...
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Open AccessOuter membrane vesicles generated by an exogenous bacteriophage lysin and protection against Acinetobacter baumannii infection
The outer membrane vesicles (OMVs) produced by Gram-negative bacteria can modulate the immune system and have great potentials for bacterial vaccine development.
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Open AccessChondroitin sulfate-modified tragacanth gum–gelatin composite nanocapsules loaded with curcumin nanocrystals for the treatment of arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease of yet undetermined etiology that is accompanied by significant oxidative stress, inflammatory responses, and damage to joint tissues. In this study, ...
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Open AccessHigh-density lipoprotein mimetic nano-therapeutics targeting monocytes and macrophages for improved cardiovascular care: a comprehensive review
The prevalence of cardiovascular diseases continues to be a challenge for global health, necessitating innovative solutions. The potential of high-density lipoprotein (HDL) mimetic nanotherapeutics in the cont...
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Open AccessMesoporous MOFs with ROS scavenging capacity for the alleviation of inflammation through inhibiting stimulator of interferon genes to promote diabetic wound healing
Excessive production of reactive oxygen species (ROS) and inflammation are the key problems that impede diabetic wound healing. In particular, dressings with ROS scavenging capacity play a crucial role in the ...
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Open AccessComprehensive dry eye therapy: overcoming ocular surface barrier and combating inflammation, oxidation, and mitochondrial damage
Dry Eye Disease (DED) is a prevalent multifactorial ocular disease characterized by a vicious cycle of inflammation, oxidative stress, and mitochondrial dysfunction on the ocular surface, all of which lead to ...
