28 Result(s)
within
Dorothy A. Thompson
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Article
Detecting Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder Using Multimodal Time-Frequency Analysis with Machine Learning Using the Electroretinogram from Two Flash Strengths
Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) are conditions that similarly alter cognitive functioning ability and challenge the social interaction, attention, and communi...
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Article
Open AccessFull-field stimulus threshold testing: a sco** review of current practice
The full-field stimulus threshold (FST) is a psychophysical measure of whole-field retinal light sensitivity. It can assess residual visual function in patients with severe retinal disease and is increasingly ...
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Article
Open AccessISCEV standard pattern reversal VEP development: paediatric reference limits from 649 healthy subjects
To establish the extent of agreement for ISCEV standard reference pattern reversal VEPs (prVEPs) acquired at three European centres, to determine any effect of sex, and to establish reference intervals from bi...
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Article
Open AccessGroup comparisons of the individual electroretinogram time trajectories for the ascending limb of the b-wave using a raw and registered time series
The electroretinogram is a clinical test commonly used in the diagnosis of retinal disorders with the peak time and amplitude of the a- and b-waves used as the main indicators of retinal function. However, sub...
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Article
Open AccessElectrophysiological assessment of nutritional optic neuropathy: a case report
To report an unexpectedly asymmetric, progressive nutritional optic neuropathy associated with vitamin A deficient optic canal hyperostosis in a 15-year-old female with a long history of a restricted diet.
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Article
Open AccessAssessment of digital light processing (DLP) projector stimulators for visual electrophysiology
Visual electrophysiology tests require the use of precise and calibrated visual display units (VDUs). Existing VDUs for presenting structured stimuli are now mostly obsolete, with modern solutions limited or u...
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Article
Open AccessElectrophysiological and fundoscopic detection of intracranial hypertension in craniosynostosis
To assess the diagnostic accuracy of fundoscopy and visual evoked potentials (VEPs) in detecting intracranial hypertension (IH) in patients with craniosynostosis undergoing spring-assisted posterior vault expa...
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Article
Open AccessThe electroretinogram b-wave amplitude: a differential physiological measure for Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder
Attention Deficit Hyperactivity Disorder (ADHD) is the most prevalent childhood neurodevelopmental disorder. It shares some genetic risk with Autism Spectrum Disorder (ASD), and the conditions often occur toge...
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Article
Visual outcomes in children with syndromic craniosynostosis: a review of 165 cases
To determine visual outcomes and prevalence of amblyogenic risk factors in children with Apert, Crouzon, Pfeiffer and Saethre-Chotzen syndromes.
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Article
Open AccessCorrection: An ERG and OCT study of neuronal ceroid lipofuscinosis CLN2 Battens retinopathy
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Article
Open AccessAn ERG and OCT study of neuronal ceroid lipofuscinosis CLN2 Battens retinopathy
Late infantile neuronal ceroid lipofuscinosis (CLN2 Batten disease) is a rare, progressive neurodegenerative disease of childhood. The natural history of motor and language regression is used to monitor the ef...
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Article
Open AccessCase report: Unilateral optic nerve aplasia and developmental hemi-chiasmal dysplasia with VEP misrouting
To describe the trans-occipital asymmetries of pattern and flash visual evoked potentials (VEPs), in an infant with MRI findings of unilateral optic nerve aplasia and hemi-chiasm dysplasia.
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Article
Pattern-onset and OFFset visual evoked potentials in the diagnosis of hemianopic field defects
Visual evoked potentials (VEPs) assess the function of the visual pathway from the retina to the primary visual cortex. There is much evidence that monocular pattern-reversal and flash VEPs can distinguish dys...
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Article
Open AccessISCEV extended protocol for VEP methods of estimation of visual acuity
The International Society for Clinical Electrophysiology of Vision (ISCEV) standard for visual evoked potentials (VEPs) describes a minimum procedure for clinical VEP testing and encourages more extensive test...
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Article
Misaligned foveal morphology and sector retinal dysfunction in AKT1-mosaic Proteus syndrome
Proteus syndrome arises as a result of a post-zygotic mosaic activating mutation in the AKT1 oncogene, causing a disproportionate overgrowth of affected tissues. A small number of ocular complications have bee...
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Article
Open AccessVEP estimation of visual acuity: a systematic review
Visual evoked potentials (VEPs) can be used to measure visual resolution via a spatial frequency (SF) limit as an objective estimate of visual acuity. The aim of this systematic review is to collate descriptio...
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Article
Light-Adapted Electroretinogram Differences in Autism Spectrum Disorder
Light-adapted (LA) electroretinograms (ERGs) from 90 individuals with autism spectrum disorder (ASD), mean age (13.0 ± 4.2), were compared to 87 control subjects, mean age (13.8 ± 4.8). LA-ERGs were produced b...
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Article
Open AccessConditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision
Irreversible photoreceptor cell death is a major cause of blindness in many retinal dystrophies. A better understanding of the molecular mechanisms underlying the progressive loss of photoreceptor cells remain...
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Article
Open AccessISCEV extended protocol for the dark-adapted red flash ERG
The International Society for Clinical Electrophysiology of Vision (ISCEV) standard for full-field electroretinography (ERG) describes a minimum procedure, but encourages more extensive testing. This ISCEV ex...
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Article
Open AccessERGs on the brain: the benefits of simultaneous flash retinal and cortical responses in paediatric cerebral visual impairment
To highlight the importance of simultaneous flash electroretinogram (ERG) and visual evoked potential (VEP) recording to differentiate a true flash VEP response from an artefact caused by the intrusion of the ...
