-
Article
Open AccessAchieving consistency of flexible surface acoustic wave sensors with artificial intelligence
Flexible surface acoustic wave technology has garnered significant attention for wearable electronics and sensing applications. However, the mechanical strains induced by random deformation of these flexible S...
-
Article
Open AccessNeoadjuvant camrelizumab (an anti-PD-1 antibody) plus chemotherapy or apatinib (a VEGFR-2 inhibitor) for initially unresectable stage II–III non-small-cell lung cancer: a multicentre, two-arm, phase 2 exploratory study
This multicentre, two-arm, phase 2 study aimed to explore the efficacy and safety of neoadjuvant camrelizumab plus chemotherapy or apatinib in patients with initially unresectable stage II–III non-small-cell l...
-
Article
Open AccessEmerging trends in sperm selection: enhancing success rates in assisted reproduction
This comprehensive review explores the evolving landscape of sperm selection techniques within the realm of Assisted Reproductive Technology (ART). Our analysis delves into a range of methods from traditional ...
-
Article
Open AccessA network meta-analysis of efficacy, acceptability, and tolerability of antipsychotics in treatment-resistant schizophrenia
Clozapine is considered as the standard treatment for this subgroup, but the evidence is not unequivocal. There are several potential alternatives being used because of the possible adverse effects of clozapin...
-
Article
Open AccessProMENDA: an updated resource for proteomic and metabolomic characterization in depression
Depression is a prevalent mental disorder with a complex biological mechanism. Following the rapid development of systems biology technology, a growing number of studies have applied proteomics and metabolomic...
-
Article
Open AccessPerceived school bullying and psychotic-like experiences in sexual minority adolescents: the mediating and moderating roles of resilience
This two-wave, longitudinal study aimed to examine the potential moderating and mediating effects of resilience on the association between perceived school bullying and psychotic-like experiences among Chinese...
-
Article
Open AccessUniversal Murray’s law for optimised fluid transport in synthetic structures
Materials following Murray’s law are of significant interest due to their unique porous structure and optimal mass transfer ability. However, it is challenging to construct such biomimetic hierarchical channel...
-
Article
Open AccessAgomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer’s disease
Adult neurogenesis occurs in the subventricular zone (SVZ) and the subgranular zone of the dentate gyrus in the hippocampus. The neuronal stem cells in these two neurogenic niches respond differently to variou...
-
Article
Open AccessModerating and mediating effects of resilience between childhood trauma and psychotic-like experiences among college students
Extensive literature revealed that childhood trauma serves as a significant risk factor for develo** psychotic-like experiences (PLEs) among the general population. Resilience has been regarded as a protecti...
-
Article
Open AccessElevating community well-being in mining areas: the proposal of the mining area sustainability index (MASI)
In response to the urgent environmental and social challenges posed by mining operations, this paper introduces the Mining Area Sustainability Index (MASI), a novel framework aimed at transforming the mining s...
-
Article
Open AccessCan aerosol optical depth unlock the future of air quality monitoring and lung cancer prevention?
This “Policy Brief” explores the potential integration of Aerosol Optical Depth (AOD) into the United Kingdom’s air quality and public health monitoring frameworks, highlighting its potential to enhance existi...
-
Article
Open AccessSingle-cell transcriptomic analysis reveals tumor cell heterogeneity and immune microenvironment features of pituitary neuroendocrine tumors
Pituitary neuroendocrine tumors (PitNETs) are one of the most common types of intracranial tumors. Currently, the cellular characteristics of normal pituitary and various other types of PitNETs are still not c...
-
Article
Open AccessWaste milk humification product can be used as a slow release nano-fertilizer
The demand for milk has increased globally, accompanied by an increase in waste milk. Here, we provide an artificial humification technology to recycle waste milk into an agricultural nano-fertilizer. We use K...
-
Article
Open AccessCorrection: circular RNA circATP9A promotes non-small cell Lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization
-
Article
Open AccessCircular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarization
CircRNA is recognized for its significant regulatory function across various cancers. However, its regulatory role in non-small cell lung cancer (NSCLC) is still largely uncharted.
-
Article
Open AccessAn individualized nomogram for predicting and validating spread through air space (STAS) in surgically resected lung adenocarcinoma: a single center retrospective analysis
A single-center study was conducted to explore the association between STAS and other clinical features in surgically resected adenocarcinoma to enhance our current understanding of STAS.
-
Article
Open AccessAntipsychotic dose, dopamine D2 receptor occupancy and extrapyramidal side-effects: a systematic review and dose-response meta-analysis
Antipsychotic drugs differ in their propensity to cause extrapyramidal side-effects (EPS), but their dose-effects are unclear. Therefore, we conducted a systematic review and dose-response meta-analysis. We se...
-
Article
Open AccessThe predictive role of psychotic-like experiences in suicidal ideation among technical secondary school and college students during the COVID-19 pandemic
Previous research has shown the strong association between psychotic-like experiences (PLEs) and suicide. However, the predictive role of PLEs in suicidal ideation (SI) during the COVID-19 pandemic remains unc...
-
Article
Open AccessA new bin size index method for statistical analysis of multimodal datasets from materials characterization
This paper presents a normalized standard error-based statistical data binning method, termed “bin size index” (BSI), which yields an optimized, objective bin size for constructing a rational histogram to faci...
-
Article
Open AccessER Ca2+ overload activates the IRE1α signaling and promotes cell survival
Maintaining homeostasis of Ca2+ stores in the endoplasmic reticulum (ER) is crucial for proper Ca2+ signaling and key cellular functions. Although Ca2+ depletion has been known to cause ER stress which in turn ac...
