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    SRP54 Negatively Regulates IFN-Beta Production and Antiviral Response by Targeting RIG-I and MDA5

    During virus infection, RIG-I-like receptors (RLRs) recognize viral RNAs and recruit the adaptor protein VISA to activate downstream signaling, leading to activation of transcription factors NF-κB and IRF3, wh...

    Dong-Peng Wang, Hong-Yan Zhang, Bo-Wei Liao, Zhen Tong, Zhi-Sheng Xu… in Virologica Sinica (2021)