4 Result(s)
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Dong Soon Choi
Biomedicine
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Article
Open AccessEvaluation of anti-PD-1-based therapy against triple-negative breast cancer patient-derived xenograft tumors engrafted in humanized mouse models
Breast cancer has been considered not highly immunogenic, and few patients benefit from current immunotherapies. However, new strategies are aimed at changing this paradigm. In the present study, we examined t...
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Article
Open AccessAntitumor activity of Cetuximab in combination with Ixabepilone on triple negative breast cancer stem cells
Develo** novel strategies against treatment-resistant triple negative breast cancer (TNBC) cells remains a significant challenge. The ErbB family, including epidermal growth factor receptor (EGFR), plays key...
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Chapter
Breast Cancer Stem Cells
Cancer stem cells (CSCs) represent a heterogeneous subpopulation of cancer cells within tumors. CSCs divide asymmetrically to generate daughter cells that either have CSC characteristics including self-renewal...
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Article
Open AccessInhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer with no effective targeted therapy. Inducible nitric oxide synthase (iNOS) is associated with poor survival in patients with breast c...
